| 1 |
hypoxia-inducible factor-alpha
(106 times)
|
Biochemistry
(20 times)
|
VHL (28 times)
PHD (10 times)
PHD2 (8 times)
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1999 Characterization of an oxygen/redox-dependent degradation domain of hypoxia-inducible factor alpha (HIF-alpha) proteins.
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| 2 |
hypoxia-inducible transcription factor-alpha
(5 times)
|
Physiology
(2 times)
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EPO (2 times)
PHD3 (2 times)
ARDs (1 time)
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2007 Placental HIF-1 alpha, HIF-2 alpha, membrane and soluble VEGF receptor-1 proteins are not increased in normotensive pregnancies complicated by late-onset intrauterine growth restriction.
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| 3 |
hypoxia-inducible factor-1alpha-subunit
(4 times)
|
Biology
(1 time)
|
ccRCCs (1 time)
ETC (1 time)
HIF (1 time)
|
2006 Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2.
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| 4 |
heterodimeric transcription factors consisting of an oxygen-sensitive alpha subunit
(1 time)
|
Cell Biology
(1 time)
|
HIFs (1 time)
|
2008 The role of hypoxia-inducible factors in tumorigenesis.
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| 5 |
HIF is a transcription factor consisting of an alpha subunit
(1 time)
|
Biochemistry
(1 time)
|
EPO (1 time)
HIF (1 time)
|
2009 Erythrocytosis-associated HIF-2alpha mutations demonstrate a critical role for residues C-terminal to the hydroxylacceptor proline.
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| 6 |
hypoxia regulated by hypoxia-inducing factor-alpha
(1 time)
|
Chemistry
(1 time)
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HIF-PHD2 (1 time)
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2018 Click Chemistry-Based Discovery of [3-Hydroxy-5-(1 H-1,2,3-triazol-4-yl)picolinoyl]glycines as Orally Active Hypoxia-Inducing Factor Prolyl Hydroxylase Inhibitors with Favorable Safety Profiles for the Treatment of Anemia.
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| 7 |
hypoxia-inducible factor-alpha family of transcription factors
(1 time)
|
Metabolism
(1 time)
|
VEGF (1 time)
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2010 Hypoxia increases Annexin A2 expression in osteoblastic cells via VEGF and ERK.
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| 8 |
hypoxia-inducible heterodimeric transcription factor
(1 time)
|
Neoplasms
(1 time)
|
RCC (1 time)
siRNA (1 time)
VHL (1 time)
|
2005 Nox4 is critical for hypoxia-inducible factor 2-alpha transcriptional activity in von Hippel-Lindau-deficient renal cell carcinoma.
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| 9 |
Hypoxia-inducible transcription factor-1alpha and -2alpha
(1 time)
|
Embryology
(1 time)
|
NP (1 time)
PE (1 time)
VHL (1 time)
|
2008 Proteasomal activity in placentas from women with preeclampsia and intrauterine growth restriction: implications for expression of HIF-alpha proteins.
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