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Abbreviation: IC50
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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
inhibitory concentration 50
(257 times)
Pharmacology
(36 times)
ROS (8 times)
DPPH (7 times)
CC50 (6 times)
1983 A simple radiometric in vitro assay for acetylcholinesterase inhibitors.
concentration causing 50% inhibition
(23 times)
Physiology
(4 times)
12-HETE (1 time)
12-HPETE (1 time)
ABEC (1 time)
1984 Platelet receptor recognition site on human fibrinogen. Synthesis and structure-function relationship of peptides corresponding to the carboxy-terminal segment of the gamma chain.
its concentrations for 50% inhibition
(18 times)
Biochemistry
(6 times)
5-HETE (2 times)
GAE (2 times)
HLM (2 times)
1982 Selective inhibition of platelet lipoxygenase by esculetin.
inhibiting cell growth by 50
(14 times)
Neoplasms
(4 times)
5-aza (1 time)
5-FU (1 time)
AR (1 time)
1984 Galactosyltransferase activity and cell growth: uridine diphosphate (UDP)galactose inhibition of murine leukemic L1210 cells.
inhibitory concentration of 50% of cells
(14 times)
Neurology
(2 times)
5-FU (1 time)
ACL (1 time)
AFM (1 time)
1990 Pharmacological and Biochemical Properties of Nicotinic Receptors from Chick Retina.
inhibit cell proliferation by 50
(9 times)
Neoplasms
(5 times)
5-FU (2 times)
TS (2 times)
COX-2 (1 time)
1989 Enhanced sensitivity of the rat hepatoma cell to the daunorubicin analogue 4-demethoxydaunorubicin associated with induction of DNA damage.
inhibiting 50% of enzyme activity
(9 times)
Toxicology
(4 times)
CA (2 times)
COX (2 times)
4-AP (1 time)
1994 Dibasic (amidinoaryl)propanoic acid derivatives as novel blood coagulation factor Xa inhibitors.
induce 50% inhibition
(7 times)
Drug Therapy
(2 times)
ACE (1 time)
ADP (1 time)
CDCA (1 time)
1987 Inhibition by amiloride of contractile elements in smooth muscle of guinea pig taenia cecum and chicken gizzard.
inhibits the enzyme activity by 50
(7 times)
Biochemistry
(2 times)
CYP2C9 (1 time)
DHFR (1 time)
MC (1 time)
1986 Thiopurine methyltransferase: structure-activity relationships for benzoic acid inhibitors and thiophenol substrates.
10  inhibitory concentration of cisplatin for 50% cell viability
(5 times)
Neoplasms
(3 times)
NSCLC (2 times)
miR-630 (1 time)
MnSOD (1 time)
2003 Growth inhibition of human tumor cell lines by withanolides from Withania somnifera leaves.
11  incorporation into DNA by 50
(4 times)
Pharmacology
(2 times)
--- 2001 Aromatic extended bisamidines: synthesis, inhibition of topoisomerases, and anticancer cytotoxicity in vitro.
12  inhibit 50% of the collagenase activity
(4 times)
Dentistry
(2 times)
BMVC (1 time)
GCF (1 time)
LJP (1 time)
1992 Tetracycline inhibition identifies the cellular origin of interstitial collagenases in human periodontal diseases in vivo.
13  induced 50% growth inhibition
(3 times)
Neoplasms
(1 time)
FCS (1 time)
G. lamblia (1 time)
HPLC (1 time)
1995 Effects of suramin on human lung cancer cell lines.
14  inhibit 50% of DPPH radicals
(3 times)
Drug Discovery
(1 time)
ABTS (1 time)
CE (1 time)
DPPH (1 time)
2018 Antioxidant activity and potential of Caesalpinia sappan aqueous extract on synthesis of silver nanoparticles.
15  inhibit the growth of HT-29 cells by 50
(3 times)
Neoplasms
(2 times)
BCRP (1 time)
EHNA (1 time)
MAIQ (1 time)
1990 Effect of ribonucleotide reductase inhibitors on the growth of human colon carcinoma HT-29 cells in culture.
16  inhibit the proliferation of cells by 50
(3 times)
Neoplasms
(2 times)
CDDP (1 time)
PNS (1 time)
1993 In vitro antitumor activity of a new platinum complex, DWA2114R against human tumor cell lines.
17  inhibited 50% of the enzymatic activity
(3 times)
Pharmacology
(2 times)
ACE (1 time)
PAF (1 time)
PDE (1 time)
1988 Relative inhibitory potency and plasma drug levels of angiotensin converting enzyme inhibitors in the rat.
18  inhibiting 50% of cell viability
(3 times)
Mycotoxins
(1 time)
ALDH1 (1 time)
ChIP (1 time)
OSCC (1 time)
2009 Trichothecene-induced cytotoxicity on human cell lines.
19  inhibiting 50% of the cellular growth
(3 times)
Communicable Diseases
(1 time)
EP (1 time)
HIV (1 time)
IC 90 (1 time)
1993 In vitro antiviral activity of didanosine compared with that of other dideoxynucleoside analogs against laboratory strains and clinical isolates of human immunodeficiency virus.
20  inhibitor causing 50% inhibition of original enzyme activity
(3 times)
Biology
(3 times)
HPLC (3 times)
CRC (2 times)
RLMs (2 times)
2019 Validation of an HPLC Method for the Simultaneous Quantification of Metabolic Reaction Products Catalysed by CYP2C11 Enzymes in Rat Liver Microsomes: In Vitro Inhibitory Effect of Salicylic Acid on CYP2C11 Enzyme.
21  inhibitory concentration of 50% of free radicals
(3 times)
Cardiology
(2 times)
STZ (3 times)
A.E.P.F.A.S (1 time)
A.P.A.E (1 time)
2017 Potent antihyperglycemic and hypoglycemic effect of Tamarix articulata Vahl. in normal and streptozotocin-induced diabetic rats.
22  inhibits color development by 50
(3 times)
Nutritional Sciences
(2 times)
ELISA (2 times)
DON (1 time)
LC (1 time)
1994 Quantitation and stability of fumonisins B1 and B2 in milk.
23  Acacetin caused 50% growth inhibition
(2 times)
Cell Biology
(1 time)
PARP (2 times)
AIF (1 time)
MAPK (1 time)
2007 Acacetin-induced apoptosis of human breast cancer MCF-7 cells involves caspase cascade, mitochondria-mediated death signaling and SAPK/JNK1/2-c-Jun activation.
24  IC50 value of 18.91 mug/ml compared to ascorbic acid
(2 times)
Pharmacology
(2 times)
EFA (1 time)
NO (1 time)
2013 Antinociceptive and antioxidant potential of the crude ethanol extract of the leaves of Ageratum conyzoides grown in Bangladesh.
25  incorporation by 50
(2 times)
Virology
(1 time)
CC50 (1 time)
EICAR (1 time)
IMP dehydrogenase (1 time)
1996 Inhibitors of infectious pancreatic necrosis virus (IPNV) replication.
26  incubation, 50% inhibitory concentrations
(2 times)
Pediatrics
(1 time)
17-AAG (1 time)
ALL (1 time)
Hz (1 time)
2005 Effects of 17-allylamino-17-demethoxygeldanamycin (17-AAG) on pediatric acute lymphoblastic leukemia (ALL) with respect to Bcr-Abl status and imatinib mesylate sensitivity.
27  induced 50% of the maximal inhibition
(2 times)
Pharmacology
(1 time)
EOPB (1 time)
NMDA (1 time)
WKY (1 time)
1995 Inhibition by propofol (2,6 di-isopropylphenol) of the N-methyl-D-aspartate subtype of glutamate receptor in cultured hippocampal neurones.
28  induces a 50% reduction of viability
(2 times)
Allergy and Immunology
(2 times)
PSMA (2 times)
2006 A recombinant PSMA-specific single-chain immunotoxin has potent and selective toxicity against prostate cancer cells.
29  inhibit 50% of the colony formation
(2 times)
Antineoplastic Agents
(1 time)
BM (1 time)
DXR (1 time)
1992 Reduced cardiotoxicity and increased cytotoxicity in a novel anthracycline analogue, 4'-amino-3'-hydroxy-doxorubicin.
30  inhibiting 50% of parasitic growth
(2 times)
Parasitology
(1 time)
ABTS (1 time)
FRAP (1 time)
ORAC (1 time)
2014 Activity of olive leaf extracts against the promastigote stage of Leishmania species and their correlation with the antioxidant activity.
31  inhibiting cell survival by 50
(2 times)
Neoplasms
(1 time)
FCS (1 time)
GST (1 time)
Pt (1 time)
1994 Effect of ultrafilterable platinum concentration on cisplatin and carboplatin cytotoxicity in human tumor and bone marrow cells in vitro.
32  inhibiting colony formation by 50
(2 times)
Hematology
(1 time)
9-AC (1 time)
CAM (1 time)
CFU-GM (1 time)
1988 Inhibition of hemopoiesis in murine marrow cell cultures by recombinant murine tumor necrosis factor alpha: evidence for long-term effects on stromal cells.
33  inhibition concentration of 50% cell growth
(2 times)
Neoplasms
(2 times)
LRP (1 time)
2010 [Effect of Bufalin on proliferation and apoptosis of human non-small cell lung cancer A549 cell].
34  inhibition of 50% of COX activity
(2 times)
Veterinary Medicine
(1 time)
CPF (1 time)
DFU (1 time)
NSAID (1 time)
2001 In vitro effects of cyclooxygenase inhibitors in whole blood of horses, dogs, and cats.
35  inhibitory concentration values of 50% of activity
(2 times)
Ticks
(1 time)
FTIR (1 time)
GSTs (1 time)
RmGST (1 time)
2017 Physicochemical Characterization and Biological Activities of the Triterpenic Mixture alpha,beta-Amyrenone.
36  initial activity by 50
(2 times)
Molecular Biology
(1 time)
AChE (1 time)
PDE (1 time)
1989 Inotropic responses to cyclic nucleotide phosphodiesterase inhibitors in immature and adult rabbit myocardium.
37  into pseudo-Hill plots and the concentrations at 50% inhibition
(2 times)
Chemistry Techniques, Analytical
(2 times)
FP (2 times)
ER (1 time)
hrER-beta (1 time)
2003 Study on interactions of endocrine disruptors with estrogen receptor-beta using fluorescence polarization.
38  steroid causing 50% inhibition
(2 times)
Pulmonary Medicine
(1 time)
HD (1 time)
HECM (1 time)
IL-2R (1 time)
1995 Comparative study of the effects of different glucocorticosteroids on eosinophil survival primed by cultured epithelial cell supernatants obtained from nasal mucosa and nasal polyps.
39  (ADP)-induced platelet aggregation with 50% inhibition
(1 time)
Hematology
(1 time)
ADP (1 time)
1992 Antithrombotic properties of L-cysteine, N-(mercaptoacetyl)-D-Tyr-Arg-Gly-Asp-sulfoxide (G4120) in a hamster platelet-rich femoral vein thrombosis model.
40  adrenaline-induced arrhythmia by 50
(1 time)
Pharmacology
(1 time)
--- 1993 Effects of gallopamil, a Ca2+ channel blocker in models of ventricular arrhythmia in dogs.
41  anti-influenza virus type A activity with 50% inhibition
(1 time)
Complementary Therapies
(1 time)
--- 2006 Phytochemical screening and antiviral activity of some medicinal plants from the island Soqotra.
42  chlorpyrifos-inhibitory concentration 50
(1 time)
Insects
(1 time)
AChE (1 time)
CarE (1 time)
CAT (1 time)
2015 Effects of chlorpyrifos on enzymatic systems of Cydia pomonella (Lepidoptera: Tortricidae) adults.
43  collagen-induced platelet aggregation by 50
(1 time)
Chemistry, Clinical
(1 time)
--- 2007 Utility of PFA-100 closure time vs. optical aggregometry in assessing the efficacy of platelet membrane glycoprotein IIb/IIIa antagonists in vitro.
44  concentration causing 50% inhibition of the initial rate of glucuronidation
(1 time)
Neoplasms
(1 time)
--- 1993 Bile acid inhibition of xenobiotic-metabolizing enzymes is a factor in the mechanism of colon carcinogenesis: tests of aspects of the concept with glucuronosyltransferase.
45  concentration causing 50% reduction of the signal intensity
(1 time)
Allergy and Immunology
(1 time)
DMPO (1 time)
OZ (1 time)
PMA (1 time)
1989 [Influences of anti-allergic drugs on superoxide generation from the hypoxanthine-xanthine oxidase system or polymorphonuclear leukocytes].
46  concentrations causing 50% cell growth inhibition
(1 time)
CTCL (1 time)
2018 Screening of ferrocenyl-phosphines identifies a gold-coordinated derivative as a novel anticancer agent for hematological malignancies.
47  concentrations causing 50% inhibition of in vitro growth of Plasmodium berghei
(1 time)
Biology
(1 time)
--- 2013 In vitro antiplasmodial activity, cytotoxicity and chemical profiles of sponge species of Cuban coasts.
48  Concentrations causing 50% inhibition of the studied steps
(1 time)
Microbiology
(1 time)
--- 2019 Anti-biofilm activity of a semi-synthetic molecule obtained from resveratrol against Candida albicans biofilm.
49  concentrations causing 50% reproductive inhibition
(1 time)
Chemistry
(1 time)
SSDs (1 time)
2016 Increasing uranium exposure durations to the aquatic snail Amerianna cumingi does not result in lower toxicity estimates.
50  copper-induced lipid hydroperoxidation of LDL by 50
(1 time)
Pharmacology
(1 time)
LDL (1 time)
1996 Inhibition of lipid hydroperoxidation of low density lipoprotein by the Ca(2+)-channel and alpha 1-adrenoceptor antagonist monatepil maleate.
51  CYP450 inhibition
(1 time)
Toxicology
(1 time)
7-HMG (1 time)
COR (1 time)
HLMs (1 time)
2019 Exploration of cytochrome P450 inhibition mediated drug-drug interaction potential of kratom alkaloids.
52  experiments causing 50% cell growth inhibition
(1 time)
Neoplasms
(1 time)
MTT (1 time)
2008 Cytotoxicity of a series of ferrocene-containing beta-diketones.
53  FHV-1-induced plaque formation by 50
(1 time)
Ophthalmology
(1 time)
--- 2013 In vitro cytotoxicity and antiviral efficacy against feline herpesvirus type 1 of famciclovir and its metabolites.
54  HSV-1-induced CPE formation by 50
(1 time)
Microbiological Phenomena
(1 time)
CPE (1 time)
HSV-1 and -2 (1 time)
2019 Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2.
55  HSV-2-infected cells, with a 50% neutralizing dilution
(1 time)
Anti-Bacterial Agents
(1 time)
HSV-2 (1 time)
2014 Antiviral activity of a single-domain antibody immunotoxin binding to glycoprotein D of herpes simplex virus 2.
56  hydrophilic compound; 50% inhibition
(1 time)
Botany
(1 time)
--- 1984 Identification of calmodulin in the green alga Mougeotia and its possible function in chloroplast reorientational movement.
57  I-DOX, and the concentration of drug that inhibited by 50
(1 time)
Neoplasms
(1 time)
AUC (1 time)
CFU-GM (1 time)
I-DOX (1 time)
1990 Pharmacology and clinical toxicity of 4'-iodo-4'-deoxydoxorubicin: an example of successful application of pharmacokinetics to dose escalation in phase I trials.
58  I. radiatus methanol extract in DPPH (81.220.50%), ABTS+
(1 time)
Biotechnology
(1 time)
--- 2021 HPLC-DAD characterization of phenolic profile and in vitro antioxidant, anticholinesterase, and antidiabetic activities of five mushroom species from Turkey.
59  I:Poly C causing a 50% inhibition
(1 time)
Pharmacology
(1 time)
--- 1998 Interferon-inducer polyriboinosinic-polyribocytidylic acid: a potent anti-gastric ulcer agent and inhibitor of the gastric proton pump in rats.
60  ic-ELISA with a 50%inhibitive concentration
(1 time)
Medicine
(1 time)
COT (1 time)
COT-BSA (1 time)
icELISA (1 time)
2021 [Preparation of an anti-cotinine monoclonal antibody and its application in immunological detection].
61  IC50 < 1 mumol x L(-1), such as toremifene citrate
(1 time)
Pharmacology
(1 time)
--- 2016 [Study of gonadal hormone drugs in blocking filovirus entry of cells in vitro].
62  IC50 = 66.7 3.6 M, followed by compound 4
(1 time)
Biological Science Disciplines
(1 time)
--- 2020 Isolation of Antidiabetic Withanolides from Withania coagulans Dunal and Their In Vitro and In Silico Validation.
63  IC50 of 0.04M comparable to SB203580
(1 time)
Biochemistry
(1 time)
--- 2019 Design and molecular modeling of novel P38alpha MAPK inhibitors targeting breast cancer, synthesized from oxygen heterocyclic natural compounds.
64  IC50 of 0.36M comparable to staurosporine
(1 time)
Biochemistry
(1 time)
--- 2020 VEGFR-2 inhibiting effect and molecular modeling of newly synthesized coumarin derivatives as anti-breast cancer agents.
65  IC50 range of (48-90 nM) compared to sorafenib
(1 time)
--- 2022 Discovery of pyrazolo[3,4-d]pyrimidine and pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine derivatives as novel CDK2 inhibitors: synthesis, biological and molecular modeling investigations.
66  IC50 results
(1 time)
Biochemistry
(1 time)
--- 2022 In Silico Studies, Biological Activities, and Anti-human Pancreatic Cancer Potential of 6-Hydroxy-4-methylcoumarin and 2,5-Dihydroxyacetophenone as Flavonoid Compounds.
67  IC50 value 12.45muM to the standard drug acarbose
(1 time)
Biochemistry
(1 time)
SAR (1 time)
2019 Design, synthesis, molecular modelling, ADME prediction and anti-hyperglycemic evaluation of new pyrazole-triazolopyrimidine hybrids as potent alpha-glucosidase inhibitors.
68  IC50 value as 47.200.3mug/mL which was higher than acarbose
(1 time)
Complementary Therapies
(1 time)
AQ (1 time)
CR (1 time)
EA (1 time)
2020 In Vitro Antioxidant and Antidiabetic Potentials of Syzygium caryophyllatum L. Alston.
69  IC50 value of 0.236 mg/mL followed by ultrasonic-assisted extraction (UAE)
(1 time)
Biology
(1 time)
DPPH (1 time)
UAE (1 time)
2020 Bioassay-Guided Different Extraction Techniques of Carica papaya (Linn.) Leaves on In Vitro Wound-Healing Activities.
70  IC50 value of 1.2muM, similar to that of CA-4
(1 time)
Chemistry
(1 time)
CA-4 (1 time)
2017 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
71  IC50 value of 3.41 muM, equivalent to that of boscalid
(1 time)
Chemistry
(1 time)
SDH (1 time)
2022 Design, Synthesis, and Fungicidal Evaluation of Novel 1,3-Benzodioxole-Pyrimidine Derivatives as Potential Succinate Dehydrogenase Inhibitors.
72  IC50 value than the standard drug acarbose
(1 time)
Biotechnology
(1 time)
--- 2022 Discovery of new 1,4-disubstituted 1,2,3-triazoles: in silico ADME profiling, molecular docking and biological evaluation studies.
73  IC50 values
(1 time)
TNBG (1 time)
2018 Synthesis and evaluation of new sterol derivatives as potential antitumor agents.
74  IC50 values against bloodstream T. brucei
(1 time)
Chemistry
(1 time)
QSAR (1 time)
SI (1 time)
2021 New Pd-Fe ferrocenyl antiparasitic compounds with bioactive 8-hydroxyquinoline ligands: a comparative study with their Pt-Fe analogues.
75  IC50 values for normal cells MCF10A
(1 time)
Medicine, Chinese Traditional
(1 time)
ADHC-AXpn (1 time)
DHC-Xpn (1 time)
2016 Novel cycloartane triterpenoid from Cimicifuga foetida (Sheng ma) induces mitochondrial apoptosis via inhibiting Raf/MEK/ERK pathway and Akt phosphorylation in human breast carcinoma MCF-7 cells.
76  IC50 values identical to that of 1
(1 time)
Chemistry
(1 time)
--- 2004 Synthesis, antiprotozoal and cytotoxic activities of new N-(3,4-dimethyl-5-isoxazolyl)-1,2-naphthoquinone-4-amino derivatives.
77  IC50 values in a range comparable to those of 1
(1 time)
Chemistry
(1 time)
--- 2004 Synthesis, antiprotozoal and cytotoxic activities of new N-(3,4-dimethyl-5-isoxazolyl)-1,2-naphthoquinone-4-amino derivatives.
78  IC50 values in the submicromolar range
(1 time)
Biochemistry
(1 time)
ROS (1 time)
SI (1 time)
2019 Pt-Fe ferrocenyl compounds with hydroxyquinoline ligands show selective cytotoxicity on highly proliferative cells.
79  IC50 values of 1-4
(1 time)
Chemistry
(1 time)
--- 2013 New ruthenium(II) arene complexes of anthracenyl-appended diazacycloalkanes: effect of ligand intercalation and hydrophobicity on DNA and protein binding and cleavage and cytotoxicity.
80  IC50 values of 10.05muM, and 11alpha-acetoxygedunin showed notable anti-inflammatory activity
(1 time)
Botany
(1 time)
--- 2021 A/D-rings-seco limonoids from the fruits of Aglaia edulis and their bioactivities.
81  IC50 values on both TbrPDEB1
(1 time)
Biochemistry
(1 time)
HAT (1 time)
2016 Synthesis and evaluation of analogs of the phenylpyridazinone NPD-001 as potent trypanosomal TbrPDEB1 phosphodiesterase inhibitors and in vitro trypanocidals.
82  IC50 values ranging from 59.4 to 116.5muM, higher than acarbose
(1 time)
Biochemistry
(1 time)
--- 2020 Tsaokopyranols A-M, 2,6-epoxydiarylheptanoids from Amomum tsao-ko and their alpha-glucosidase inhibitory activity.
83  IC50 values were as follows: EDPhP
(1 time)
Biochemistry
(1 time)
CDPhP (1 time)
EDPHP (1 time)
OPEs (1 time)
2020 Inhibitory effects of organophosphate esters on carboxylesterase activity of rat liver microsomes.
84  IC50 were determined for thetinctures A and B
(1 time)
MIC (1 time)
2018 Chemical and microbiological characterization of tinctures and microcapsules loaded with Brazilian red propolis extract.
85  IC50, and in DU4475 cells treated with drug A
(1 time)
Diagnostic Imaging
(1 time)
CLPS (1 time)
2001 1H NMR visible lipids are induced by phosphonium salts and 5-fluorouracil in human breast cancer cells.
86  IC50,app
(1 time)
Toxicology
(1 time)
BG (1 time)
DHBG (1 time)
EGCG (1 time)
2021 Evaluation system for cell-permeable CYP3A4 inhibitory activity using 1alpha,25-dihydroxy-vitamin D3-induced intestinal cell lines.
87  IC50. hMSCs demonstrated the lowest sensitivity to propolis
(1 time)
Biology
(1 time)
hMSCs (1 time)
MED (1 time)
2021 Exploring the anticancer effects of standardized extracts of poplar-type propolis: In vitro cytotoxicity toward cancer and normal cell lines.
88  IC50=1.94 mug/ml, which is comparable to that of nalidixic acid
(1 time)
Biochemistry
(1 time)
--- 2018 Synthesis, antimicrobial activity and molecular modeling study of 3-(5-amino-(2H)-1,2,4-triazol-3-yl]-naphthyridinones as potential DNA-gyrase inhibitors.
89  IC50pre
(1 time)
Biochemistry
(1 time)
QSAR (1 time)
2019 Virtual design of novel Plasmodium falciparum cysteine protease falcipain-2 hybrid lactone-chalcone and isatin-chalcone inhibitors probing the S2 active site pocket.
90  IC50s <20mug/ml, seven were against T. b. rhodesiense
(1 time)
Pharmacology
(1 time)
SI (1 time)
SIs (1 time)
2018 In vitro antiplasmodial, antitrypanosomal and antileishmanial activities of selected medicinal plants from Ugandan flora: Refocusing into multi-component potentials.
91  IC50s comparable to that of artemisinin
(1 time)
Chemistry
(1 time)
--- 2015 Structure-activity relationship of hybrids of Cinchona alkaloids and bile acids with invitro antiplasmodial and antitrypanosomal activities.
92  icELISA possesses a concentration of producing 50% inhibition
(1 time)
Chemistry
(1 time)
CAP (1 time)
icELISA (1 time)
2013 Development of a sensitive monoclonal antibody-based indirect competitive enzyme-linked immunosorbent assay for analysing chlorantraniliprole residues.
93  idarubicin concentration resulting in 50% inhibition
(1 time)
Neoplasms
(1 time)
--- 1988 Phase I clinical trial of orally administered 4-demethoxydaunorubicin (idarubicin) with pharmacokinetic and in vitro drug sensitivity testing in children with refractory leukemia.
94  IFNbeta that reduced viral replication in vitro by 50
(1 time)
Medicine
(1 time)
ART (1 time)
2021 Heightened resistance to host type 1 interferons characterizes HIV-1 at transmission and after antiretroviral therapy interruption.
95  II at the apparent concentrations producing 50% inhibition
(1 time)
Physiology
(1 time)
UII (1 time)
1987 Contraction of major artery segments of rat by fish neuropeptide urotensin II.
96  II that caused 50% inhibition
(1 time)
Chemistry
(1 time)
cdELISA (1 time)
ciELISA (1 time)
KLH (1 time)
2006 A sensitive enzyme-linked immunosorbent assay for detecting carcinogenic aristolochic acid in herbal remedies.
97  IK with concentration needed to obtain 50% of the block
(1 time)
Drug Therapy
(1 time)
hERG (1 time)
1998 Blockade of HERG and Kv1.5 by ketoconazole.
98  IL5RA, the 50% concentration of inhibition
(1 time)
Cell Death
(1 time)
IL5RA (1 time)
JMJD2C (1 time)
MDM2 (1 time)
2022 JMJD2C mediates the MDM2/p53/IL5RA axis to promote CDDP resistance in uveal melanoma.
99  imatinib-mediated apoptosis with a concentration inhibiting growth by 50
(1 time)
Neoplasms
(1 time)
CI (1 time)
SCF (1 time)
2002 Potential use of imatinib in Ewing's Sarcoma: evidence for in vitro and in vivo activity.
100  IMI binding to the Drosophila or Musca nAChR by 50
(1 time)
Biochemistry
(1 time)
IMI (1 time)
nAChR (1 time)
1997 Synthesis of a novel [125I]neonicotinoid photoaffinity probe for the Drosophila nicotinic acetylcholine receptor.