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Abbreviation: KO
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Long forms: 268

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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
knockout
(9576 times)
Neurology
(1189 times)
WT (3626 times)
IL (252 times)
HFD (167 times)
1992 CT of 338 active professional boxers.
knockout mice
(111 times)
Neurology
(19 times)
WT (57 times)
HFD (5 times)
NO (5 times)
1998 Tenascin-C promotes healing of Habu-snake venom-induced glomerulonephritis: studies in knockout congenic mice and in culture.
KEGG Orthology
(60 times)
Biochemistry
(12 times)
GO (15 times)
DGE (6 times)
KEGG (6 times)
2003 The KEGG resource for deciphering the genome.
krill oil
(50 times)
Nutritional Sciences
(14 times)
FO (20 times)
EPA (14 times)
DHA (13 times)
1994 Effects of n-3 and n-6 fatty acids on the activities and expression of hepatic antioxidant enzymes in autoimmune-prone NZBxNZW F1 mice.
Knock-out
(36 times)
Molecular Biology
(5 times)
WT (12 times)
ANXA1 (2 times)
DG (2 times)
2005 beta-Minor globin gene expression is preferentially reduced in EKLF Knock-Out mice.
PPARalpha-knockout
(23 times)
Pathology
(5 times)
WT (10 times)
PPARalpha (3 times)
nAChRs (2 times)
1999 Role of tumor necrosis factor-alpha in Mycobacterium-induced granuloma formation in tumor necrosis factor-alpha-deficient mice.
double-knockout
(22 times)
Endocrinology
(3 times)
WT (3 times)
MT (2 times)
8-OHdG (1 time)
2000 Protective role of interleukin-1 in mycobacterial infection in IL-1 alpha/beta double-knockout mice.
gene-knockout
(21 times)
Allergy and Immunology
(5 times)
WT (4 times)
AChR (2 times)
EAMG (2 times)
2000 Suppression of experimental autoimmune myasthenia gravis in IL-10 gene-disrupted mice is associated with reduced B cells and serum cytotoxicity on mouse cell line expressing AChR.
DGKeta-knockout
(13 times)
Brain
(3 times)
WT (5 times)
DGK (4 times)
OCD (2 times)
2009 Prototypic GABA(A) receptor agonist muscimol acts preferentially through forebrain high-affinity binding sites.
10  ent-kaurene oxidase
(13 times)
Physiology
(4 times)
KS (5 times)
CPS (4 times)
GA3ox (4 times)
2004 The pea gene LH encodes ent-kaurene oxidase.
11  IFNgamma-knockout
(12 times)
Rheumatology
(2 times)
WT (6 times)
IFN-gamma (3 times)
PPARgamma (3 times)
2004 Mucosal mast cell-derived chondroitin sulphate levels in and worm expulsion from FcRgamma-knockout mice following oral challenge with Strongyloides venezuelensis.
12  single-knockout
(10 times)
Biochemistry
(3 times)
WT (5 times)
DKO (2 times)
AR (1 time)
2004 Cholinergic stimulation of salivary secretion studied with M1 and M3 muscarinic receptor single- and double-knockout mice.
13  knocking out
(8 times)
Neurology
(3 times)
8-oxodG (1 time)
AANAT (1 time)
AC (1 time)
2010 The beta-blocker atenolol lowers the longevity-related degree of fatty acid unsaturation, decreases protein oxidative damage, and increases extracellular signal-regulated kinase signaling in the heart of C57BL/6 mice.
14  keratosis obturans
(7 times)
Otolaryngology
(7 times)
EACC (6 times)
18 ears (1 time)
CT (1 time)
2003 [Erosion of the mastoid caused by the external auditory canal cholesteatoma (with 3 cases reported)].
15  knee osteoarthritis
(7 times)
Medicine
(2 times)
KOOS (3 times)
DN (1 time)
FM (1 time)
2007 Quality of life assessments with SF 36 in different musculoskeletal diseases.
16  adiponectin-knockout
(6 times)
Gastroenterology
(3 times)
WT (4 times)
NASH (2 times)
AdipoR1 (1 time)
2003 Association of hypoadiponectinemia with impaired vasoreactivity.
17  ghrelin-knockout
(6 times)
Endocrinology
(2 times)
WT (3 times)
MI (2 times)
CSNA (1 time)
2012 Ghrelin prevents incidence of malignant arrhythmia after acute myocardial infarction through vagal afferent nerves.
18  knockdown
(6 times)
Chemistry, Pharmaceutical
(1 time)
19S RP (1 time)
A1R (1 time)
ANXA4 (1 time)
2009 Roles of proteasomal 19S regulatory particles in promoter loading of thyroid hormone receptor.
19  K epoxide
(5 times)
Hematology
(2 times)
VKD (2 times)
TALENs (1 time)
TM (1 time)
2013 Evaluation of warfarin resistance using transcription activator-like effector nucleases-mediated vitamin K epoxide reductase knockout HEK293 cells.
20  kidney-only
(5 times)
Transplantation
(2 times)
DGF (3 times)
DFU (2 times)
MO (2 times)
1989 Influence of cadaveric organ source on delayed renal allograft function.
21  kinetic occipital
(5 times)
Brain
(2 times)
fMRI (2 times)
LO (2 times)
STS (1 time)
1997 The kinetic occipital region in human visual cortex.
22  knockdown or knockout
(5 times)
Neurosciences
(2 times)
ASM (1 time)
BM (1 time)
CI (1 time)
2015 Specificity of arrestin subtypes in regulating airway smooth muscle G protein-coupled receptor signaling and function.
23  receptor-knockout
(5 times)
Physiology
(2 times)
WT (3 times)
AD (1 time)
CCh (1 time)
2002 Vascular endothelin-B receptor system in vivo plays a favorable inhibitory role in vascular remodeling after injury revealed by endothelin-B receptor-knockout mice.
24  CARD3-knockout
(4 times)
Cardiology
(2 times)
WT (3 times)
CARD3 (2 times)
Ad-CTRP9 (1 time)
2013 CARD3 deficiency exacerbates diet-induced obesity, hepatosteatosis, and insulin resistance in male mice.
25  kaurene oxidase
(4 times)
Genetics
(1 time)
GA (1 time)
KAH (1 time)
rAtKO (1 time)
2006 Spatial organisation of four enzymes from Stevia rebaudiana that are involved in steviol glycoside synthesis.
26  KO mice
(4 times)
Physiology
(2 times)
WT (5 times)
BBB (1 time)
COX (1 time)
2009 Reduced SERCA2 abundance decreases the propensity for Ca2+ wave development in ventricular myocytes.
27  Kolliker's organ
(4 times)
Audiology
(2 times)
TM (2 times)
CN (1 time)
Hh (1 time)
1991 Incorporation of D-[3H]-glucosamine and L-[3H]-fucose into the developing rat cochlea.
28  Korean Oge
(4 times)
Veterinary Medicine
(1 time)
WL (2 times)
AI (1 time)
dead (1 time)
2012 Cryopreservation of Korean Oge chicken semen using N-methylacetamide.
29  Kusabira-Orange
(4 times)
Biotechnology
(2 times)
AFM (1 time)
BiFC (1 time)
FPs (1 time)
2008 A new red fluorescent protein that allows efficient marking of murine hematopoietic stem cells.
30  miR-451a-knockout
(4 times)
Cell Death
(1 time)
miRs (2 times)
WT (2 times)
ASO (1 time)
2018 Ablation of miR-146b in mice causes hematopoietic malignancy.
31  5-HT1B-knockout
(3 times)
Science
(1 time)
WT (2 times)
2000 Impaired hippocampal-dependent learning and functional abnormalities in the hippocampus in mice lacking serotonin(1A) receptors.
32  Ano5-knockout
(3 times)
Internal Medicine
(1 time)
ANO5 (3 times)
LGMD2L (2 times)
ALP (1 time)
2015 Genetic disruption of Ano5 in mice does not recapitulate human ANO5-deficient muscular dystrophy.
33  Bcl6-knockout
(3 times)
Allergy and Immunology
(2 times)
WT (2 times)
BM (1 time)
cDCs (1 time)
2001 CD4+ T cell recognition of a single discordant HLA-A2-transgenic molecule through the indirect antigen presentation pathway induces acute rejection of murine cardiac allografts.
34  DNAJA4-knockout
(3 times)
Dermatology
(2 times)
CA (2 times)
CLU (1 time)
HPV (1 time)
2018 DNAJA4 deficiency enhances NF-kappa B-related growth arrest induced by hyperthermia in human keratinocytes.
35  LRRK2-knockout
(3 times)
Neurosciences
(1 time)
LRRK2 (3 times)
PD (2 times)
WT (2 times)
2016 Leucine-rich repeat kinase 2 (LRRK2) regulates alpha-synuclein clearance in microglia.
36  MyD88-knockout
(3 times)
Gynecology
(1 time)
WT (2 times)
CH (1 time)
DC (1 time)
2008 Adjuvant effect of lipopolysaccharide on the induction of contact hypersensitivity to haptens in mice.
37  PTPMEG-knockout
(3 times)
Neurology
(1 time)
FH (1 time)
mPGES-1 (1 time)
PCs (1 time)
2007 Involvement of protein-tyrosine phosphatase PTPMEG in motor learning and cerebellar long-term depression.
38  Aire-knockout
(2 times)
Biochemistry
(1 time)
AMPK (1 time)
Cirp (1 time)
LKB1 (1 time)
2020 Aire Gene Influences the Length of the 3' UTR of mRNAs in Medullary Thymic Epithelial Cells.
39  Aldh2-knockout
(2 times)
Pharmacology
(1 time)
ALDH2 (2 times)
ACE (1 time)
WT (1 time)
2014 Impact of chronic low to moderate alcohol consumption on blood lipid and heart energy profile in acetaldehyde dehydrogenase 2-deficient mice.
40  aralar-knock-out
(2 times)
Neurology
(1 time)
Asp (1 time)
beta-OHB (1 time)
DA (1 time)
2020 βOHB Protective Pathways in Aralar-KO Neurons and Brain: An Alternative to Ketogenic Diet.
41  Bmal1-knockout
(2 times)
Cardiology
(1 time)
BPA (1 time)
2012 Increased superoxide and endothelial NO synthase uncoupling in blood vessels of Bmal1-knockout mice.
42  Cyp27b1-knockout
(2 times)
Allergy and Immunology
(1 time)
VDR (1 time)
2017 Endogenous Calcitriol Synthesis Controls the Humoral IgE Response in Mice.
43  DGKepsilon-knockout
(2 times)
Cardiology
(1 time)
Col Ialpha1 (1 time)
COX-2 (1 time)
DG (1 time)
2005 Increased collagen deposition and diastolic dysfunction but preserved myocardial hypertrophy after pressure overload in mice lacking PKCepsilon.
44  Dicer-knockout
(2 times)
Virus Physiological Phenomena
(1 time)
miRNAs (2 times)
DGCR8 (1 time)
ESCs (1 time)
2010 RNA Genes: Retroelements and Virally Retroposable microRNAs in Human Embryonic Stem Cells.
45  E-selectin-knock out
(2 times)
Cell Biology
(1 time)
BBB (1 time)
ECs (1 time)
FITC (1 time)
2002 SA-Lea and tumor metastasis: the old prediction and recent findings.
46  EGFL7-knockout
(2 times)
Endocrinology
(1 time)
BBB (1 time)
EAE (1 time)
ECM (1 time)
2018 EGFL7 reduces CNS inflammation in mouse.
47  Fgf21-knockout
(2 times)
Nutritional Sciences
(1 time)
FGF21 (2 times)
AT (1 time)
BAT (1 time)
2015 Rapid increase in fibroblast growth factor 21 in protein malnutrition and its impact on growth and lipid metabolism.
48  Karanja oil
(2 times)
Biochemistry
(1 time)
FFA (1 time)
GAFF (1 time)
KOME (1 time)
2017 Viscous Flow Behaviour of Karanja Oil Based Bio-lubricant Base Oil.
49  KEGG ortholog groups
(2 times)
Biotechnology
(1 time)
GO (2 times)
PPI (2 times)
2009 Pairwise alignment of interaction networks by fast identification of maximal conserved patterns.
50  kerosene oil
(2 times)
Diagnostic Imaging
(1 time)
DO (1 time)
EO (1 time)
MHD (1 time)
2016 A new approach involving a multi transducer ultrasonic system for cleaning turbine engines' oil filters under practical conditions.
51  kinetic occipital area
(2 times)
Neurology
(2 times)
AM (1 time)
fMRI (1 time)
2003 Responses of extrastriate cortex to switching perception of ambiguous visual motion stimuli.
52  Kingsley Olmsted
(2 times)
Medicine
(1 time)
--- 2020 Femoral Anteversion Angles in Dry Bones of Adult Nigerians: A Comparison of Two Methods.
53  knockout animals
(2 times)
Cell Communication
(1 time)
Ihh (1 time)
mGlu (1 time)
2011 Opposing efficacy of group III mGlu receptor activators, LSP1-2111 and AMN082, in animal models of positive symptoms of schizophrenia.
54  Knockouts
(2 times)
Toxicology
(1 time)
4-ABP (1 time)
BaP (1 time)
CSC (1 time)
2005 Impact of Cyp1a2 or Ahr gene knockout in mice: implications for biomonitoring studies.
55  knowledge only
(2 times)
Violence
(1 time)
DV (1 time)
2018 Project Date SMART: a Dating Violence (DV) and Sexual Risk Prevention Program for Adolescent Girls with Prior DV Exposure.
56  Korean
(2 times)
Pediatrics
(1 time)
AA (1 time)
ACEI (1 time)
BP (1 time)
2009 Questionnaire survey on pediatric hypertension in Japan and Korea.
57  KRTE only group
(2 times)
Complementary Therapies
(1 time)
AO (2 times)
KRTE (2 times)
WL (2 times)
2011 Interaction and efficacy of Keigai-rengyo-to extract and acupuncture in male patients with acne vulgaris: a study protocol for a randomized controlled pilot trial.
58  LECT2-knockout
(2 times)
Cell Membrane
(1 time)
EGFR (1 time)
HPLC (1 time)
LECT2 (1 time)
2018 Leukocyte Cell-Derived Chemotaxin 2 Retards Non-Small Cell Lung Cancer Progression Through Antagonizing MET and EGFR Activities.
59  Mecp2-knockout
(2 times)
Biological Science Disciplines
(1 time)
RTT (2 times)
GLS (1 time)
Gsk3b (1 time)
2018 Inhibition of Gsk3b Reduces Nfkb1 Signaling and Rescues Synaptic Activity to Improve the Rett Syndrome Phenotype in Mecp2-Knockout Mice.
60  MLKL-knockout
(2 times)
Biological Science Disciplines
(1 time)
MLKL (1 time)
NAFLD (1 time)
2019 ELKS/Voltage-Dependent Ca2+ Channel-beta Subunit Module Regulates Polarized Ca2+ Influx in Pancreatic beta Cells.
61  NBCe1-knockout
(2 times)
Physiology
(1 time)
WT (2 times)
apoA-I (1 time)
CA (1 time)
2007 Biogenesis of HDL by SAA is dependent on ABCA1 in the liver in vivo.
62  Nucling-knockout
(2 times)
Neoplasms
(1 time)
WT (2 times)
APCs (1 time)
cIAP (1 time)
2009 Inflammatory disease and cancer with a decrease in Kupffer cell numbers in Nucling-knockout mice.
63  PINK1-knockout
(2 times)
Neurology
(1 time)
PD (2 times)
PINK1 (2 times)
CNTF (1 time)
2013 PINK1 deficiency attenuates astrocyte proliferation through mitochondrial dysfunction, reduced AKT and increased p38 MAPK activation, and downregulation of EGFR.
64  Slitrk6-knockout
(2 times)
Physiology
(1 time)
ABR (1 time)
ARE (1 time)
BACH1 (1 time)
2011 Impaired auditory-vestibular functions and behavioral abnormalities of Slitrk6-deficient mice.
65  Speg-knockout
(2 times)
Pathology
(1 time)
CNMs (1 time)
SPEG (1 time)
WT (1 time)
2020 Striated Preferentially Expressed Protein Kinase (SPEG)-Deficient Skeletal Muscles Display Fewer Satellite Cells with Reduced Proliferation and Delayed Differentiation.
66  Spin90-knockout
(2 times)
Neurosciences
(1 time)
ABPs (1 time)
CAFs (1 time)
ECM (1 time)
2017 SPIN90 Modulates Long-Term Depression and Behavioral Flexibility in the Hippocampus.
67  TWEAK-knockout
(2 times)
Muscle, Skeletal
(1 time)
PGC-1alpha (2 times)
Tg (1 time)
TNF (1 time)
2013 TWEAK promotes exercise intolerance by decreasing skeletal muscle oxidative phosphorylation capacity.
68  znt7-knockout
(2 times)
Cells
(1 time)
12-HETE (1 time)
FABP3 (1 time)
znt7 (1 time)
2018 Aberrant fatty acid metabolism in skeletal muscle contributes to insulin resistance in zinc transporter 7 (znt7)-knockout mice.
69  (FXIIIA)-knockout
(1 time)
Hematology
(1 time)
FXIII (1 time)
2003 Factor XIII A subunit-deficient mice developed severe uterine bleeding events and subsequent spontaneous miscarriages.
70  4-1BB-knockout
(1 time)
Neurology
(1 time)
HSCs (1 time)
JE (1 time)
2015 Amelioration of Japanese encephalitis by blockage of 4-1BB signaling is coupled to divergent enhancement of type I/II IFN responses and Ly-6C(hi) monocyte differentiation.
71  ABCB5-knocked-out
(1 time)
Neoplasms
(1 time)
AC (1 time)
ICs (1 time)
MPM (1 time)
2019 Wnt/IL-1beta/IL-8 autocrine circuitries control chemoresistance in mesothelioma initiating cells by inducing ABCB5.
72  abcg2-knockout
(1 time)
Neurology
(1 time)
ABC (1 time)
CSFE (1 time)
EAE (1 time)
2020 Functional relevance of the multi-drug transporter abcg2 on teriflunomide therapy in an animal model of multiple sclerosis.
73  acrosin-knockout
(1 time)
Science
(1 time)
--- 2020 Acrosin is essential for sperm penetration through the zona pellucida in hamsters.
74  Actn3-knockout
(1 time)
Physiology
(1 time)
CSA (1 time)
2014 ACTN3 genotype and modulation of skeletal muscle response to exercise in human subjects.
75  Adam12-knockout
(1 time)
Pathology
(1 time)
ADAM12 (1 time)
CRISPR (1 time)
2019 Involvement of ADAM12 in Chondrocyte Differentiation by Regulation of TGF-beta1-Induced IGF-1 and RUNX-2 Expressions.
76  ADAMTS-1-knockout
(1 time)
Rheumatology
(1 time)
AIA (1 time)
mRNA (1 time)
RT-PCR (1 time)
2005 ADAMTS-1-knockout mice do not exhibit abnormalities in aggrecan turnover in vitro or in vivo.
77  alpha-catenin-knockout
(1 time)
Cell Biology
(1 time)
AJs (1 time)
PM (1 time)
TJs (1 time)
2018 Adherens junctions influence tight junction formation via changes in membrane lipid composition.
78  alpha-ketooctanoic
(1 time)
Pharmacology
(1 time)
KC (1 time)
KIC (1 time)
KIV (1 time)
1975 Effects of alpha-ketomonocarboxylic acids upon insulin secretion and metabolism of isolated pancreatic islets.
79  AmeloD-knockout
(1 time)
Biochemistry
(1 time)
bHLH (1 time)
Epfn (1 time)
IEE (1 time)
2018 The transcription factor AmeloD stimulates epithelial cell motility essential for tooth morphology.
80  amelogenin-knockout
(1 time)
Dentistry
(1 time)
LRAP (1 time)
TRAP (1 time)
WT (1 time)
2006 Amelogenin-mediated regulation of osteoclastogenesis, and periodontal cell proliferation and migration.
81  AMPKalpha2-knockout
(1 time)
Pharmacology
(1 time)
AMPK (1 time)
beta-AR (1 time)
ISO (1 time)
2016 Exacerbated cardiac fibrosis induced by beta-adrenergic activation in old mice due to decreased AMPK activity.
82  AMPKgamma3-knockout
(1 time)
Endocrinology
(1 time)
AMPK (1 time)
EDL (1 time)
2009 Role of the AMPKgamma3 isoform in hypoxia-stimulated glucose transport in glycolytic skeletal muscle.
83  ANXA2-knockout
(1 time)
Tropical Medicine
(1 time)
ANXA2 (1 time)
BBB (1 time)
WT (1 time)
2020 Annexin A2 depletion exacerbates the intracerebral microhemorrhage induced by acute rickettsia and Ebola virus infections.
84  AnxA6-knockout
(1 time)
Medicine
(1 time)
AnxA6 (1 time)
HDL (1 time)
HFD (1 time)
2018 Altered hepatic glucose homeostasis in AnxA6-KO mice fed a high-fat diet.
85  APOE-KO
(1 time)
Natural Science Disciplines
(1 time)
APOE (2 times)
BBB (1 time)
CCI (1 time)
2017 ApoE Influences the Blood-Brain Barrier Through the NF-kappaB/MMP-9 Pathway After Traumatic Brain Injury.
86  ApoE-single-knockout
(1 time)
Physiology
(1 time)
APOE (1 time)
2013 Mas receptor deficiency is associated with worsening of lipid profile and severe hepatic steatosis in ApoE-knockout mice.
87  AQP2-CNT-KO mice
(1 time)
Physiology
(1 time)
AQP2 (1 time)
BW (1 time)
CD (1 time)
2013 Genetic ablation of aquaporin-2 in the mouse connecting tubules results in defective renal water handling.
88  B3GALT5-knockout
(1 time)
Science
(1 time)
B3GALT5 (1 time)
GSL (1 time)
hESCs (1 time)
2020 B3GALT5 knockout alters gycosphingolipid profile and facilitates transition to human naïve pluripotency.
89  Bbc3-knockout
(1 time)
Endocrinology
(1 time)
4-HNE (1 time)
HMGB1 (1 time)
2016 Involvement of a proapoptotic gene (BBC3) in islet injury mediated by cold preservation and rewarming.
90  Beclin1-Knockout
(1 time)
Biochemistry
(1 time)
mESCs (1 time)
2021 Understanding the role of Beclin1 in mouse embryonic stem cell differentiation through CRISPR-Cas9-mediated gene editing.
91  bHLH106-knockout
(1 time)
Medicine
(1 time)
GFP (1 time)
OX (1 time)
stc8 (1 time)
2015 bHLH106 Integrates Functions of Multiple Genes through Their G-Box to Confer Salt Tolerance on Arabidopsis.
92  BKB1-R-knockout
(1 time)
Biochemistry
(1 time)
BK (1 time)
STZ (1 time)
WT (1 time)
2005 Absence of diabetic hyperalgesia in bradykinin B1 receptor-knockout mice.
93  BPLF1-knockout
(1 time)
Microbiology
(1 time)
EBV (1 time)
NPC (1 time)
PTLD (1 time)
2015 Knockout of Epstein-Barr virus BPLF1 retards B-cell transformation and lymphoma formation in humanized mice.
94  Brn-3b-knockout
(1 time)
Cell Biology
(1 time)
SHH (1 time)
TF (1 time)
2021 Linking metabolic dysfunction with cardiovascular diseases: Brn-3b/POU4F2 transcription factor in cardiometabolic tissues in health and disease.
95  C11ORF74-knockout
(1 time)
Biochemistry
(1 time)
GPCRs (1 time)
2018 C11ORF74 interacts with the IFT-A complex and participates in ciliary BBSome localization.
96  CaMKIV-knockout
(1 time)
Neurology
(1 time)
CaMKIV (1 time)
CREB (1 time)
2006 Evidence for a role of CaMKIV in the development of opioid analgesic tolerance.
97  caspase-1-knockout
(1 time)
Cardiology
(1 time)
IL-1beta (1 time)
MI (1 time)
MMP-3 (1 time)
2003 Targeted deletion of caspase-1 reduces early mortality and left ventricular dilatation following myocardial infarction.
98  catalase-knockout
(1 time)
Biochemistry
(1 time)
3-AT (1 time)
NAC (1 time)
ROS (1 time)
2021 Catalase deficiency induces reactive oxygen species mediated pexophagy and cell death in the liver during prolonged fasting.
99  Ccn4-knock out
(1 time)
Metabolism
(1 time)
hBMSCs (1 time)
siCCN4 (1 time)
TGF-beta3 (1 time)
2015 CCN4/WISP-1 positively regulates chondrogenesis by controlling TGF-beta3 function.
100  CD200R1-knockout
(1 time)
Neurology
(1 time)
CD200R1 (1 time)
WT (1 time)
2019 CD200-CD200R1 inhibitory signaling prevents spontaneous bacterial infection and promotes resolution of neuroinflammation and recovery after stroke.