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Abbreviation: LC3
Appearance Frequency: 1870 time(s)
Long forms: 48

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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
light chain 3
(1724 times)
Cell Biology
(178 times)
mTOR (167 times)
3-MA (131 times)
ROS (121 times)
1986 Monoclonal antibodies distinguish between the head portions of two myosin isozymes from chicken breast muscle.
LC3-II
(39 times)
Cell Biology
(9 times)
3-MA (3 times)
CQ (2 times)
ERK (2 times)
2008 LC3 and Autophagy.
light chain 3 alpha
(22 times)
Molecular Biology
(6 times)
EMT (2 times)
GABARAP (2 times)
mTOR (2 times)
2011 Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells.
light chain 3 beta
(15 times)
Molecular Biology
(3 times)
LDs (2 times)
ALP (1 time)
AmAtg2B (1 time)
2011 Autophagy may precede cellular senescence of bile ductular cells in ductular reaction in primary biliary cirrhosis.
light-chain protein 3
(7 times)
Reproductive Medicine
(4 times)
3-MA (1 time)
AIF (1 time)
ATG7 (1 time)
2009 The variable expression of lectin-like oxidized low-density lipoprotein receptor (LOX-1) and signs of autophagy and apoptosis in freshly harvested human granulosa cells depend on gonadotropin dose, age, and body weight.
L chain 3
(5 times)
Allergy and Immunology
(4 times)
ATG (1 time)
DC (1 time)
ER (1 time)
2011 Temporal regulation of intracellular organelle homeostasis in T lymphocytes by autophagy.
levels of microtubuleassociated protein 1A/1Blight chain 3
(4 times)
Molecular Biology
(4 times)
TEM (2 times)
AMPK (1 time)
ATG7 (1 time)
2014 Lycopene protects against apoptosis in hypoxia/reoxygenation‑induced H9C2 myocardioblast cells through increased autophagy.
light chain 3 fusion protein
(4 times)
Medicine
(4 times)
PARP (2 times)
CQ (1 time)
DMSO (1 time)
2016 [Sunitinib induces autophagy via suppressing Akt/mTOR pathway in renal cell carcinoma].
light chain 3 protein
(4 times)
Neoplasms
(2 times)
7-KC (1 time)
BM (1 time)
bort (1 time)
2009 Oxidized low-density lipoproteins upregulate proline oxidase to initiate ROS-dependent autophagy.
10  MAP1-LC3
(3 times)
Cell Biology
(2 times)
FACS (2 times)
UBL (2 times)
IBM (1 time)
2008 Utilizing flow cytometry to monitor autophagy in living mammalian cells.
11  LC3-I and LC3-II
(2 times)
Pathology
(1 time)
mTHPC (1 time)
2015 Piwil 2 gene transfection changes the autophagy status in a rat model of diabetic nephropathy.
12  light chain 3 of MAP1A/B
(2 times)
Neurology
(1 time)
ATG8 (1 time)
LRPPRC (1 time)
MAP (1 time)
2008 Morphological and biochemical signs of age-related neurodegenerative changes in klotho mutant mice.
13  light chain microtubule-associated protein 3
(2 times)
Lipids
(2 times)
SIRT1 (2 times)
circLDLR (1 time)
circRNAs (1 time)
2018 Erythropoietin alleviates hepatic steatosis by activating SIRT1-mediated autophagy.
14  Long chain 3
(2 times)
Oncogenes
(1 time)
BME (1 time)
2017 Paris saponin-induced autophagy promotes breast cancer cell apoptosis via the Akt/mTOR signaling pathway.
15  mitochondria-light chain 3
(2 times)
Cells
(1 time)
GABARAPL1 (2 times)
STBD1 (2 times)
AA (1 time)
2021 Asiatic acid alleviates ischemic myocardial injury in mice by modulating mitophagy- and glycophagy-based energy metabolism.
16  1B-light chain 3-phosphatidylethanolamine conjugate
(1 time)
Brain
(1 time)
AD (1 time)
APP (1 time)
BDNF (1 time)
2022 Epigenetic regulation and autophagy modulation debilitates insulin resistance associated Alzheimer's disease condition in rats.
17  co-localized with MAP1LC3
(1 time)
Neurology
(1 time)
AS (1 time)
HD (1 time)
HTT (1 time)
2019 HAP1 is an in vivo UBE3A target that augments autophagy in a mouse model of Angelman syndrome.
18  II-Light Chain 3
(1 time)
Biology
(1 time)
HSP70 (1 time)
LAMP1 (1 time)
2022 Within the Ischemic Penumbra, Sub-Cellular Compartmentalization of Heat Shock Protein 70 Overlaps with Autophagy Proteins and Fails to Merge with Lysosomes.
19  L chain protein 3
(1 time)
Allergy and Immunology
(1 time)
--- 2012 Helminth infection impairs autophagy-mediated killing of bacterial enteropathogens by macrophages.
20  La(OH)3-cellulose
(1 time)
Nanotechnology
(1 time)
LC (1 time)
2014 Cellulose-lanthanum hydroxide nanocomposite as a selective marker for detection of toxic copper.
21  lamprey complement component C3
(1 time)
Allergy and Immunology
(1 time)
LC1q (1 time)
LC1q MO (1 time)
MBL (1 time)
2020 Complement component C1q plays a critical role in VLRA/VLRC-mediated immune response.
22  Latent Class 3
(1 time)
Psychology
(1 time)
LC1 (1 time)
LC2 (1 time)
PCL-R (1 time)
2015 Variants of psychopathy in adult male offenders: A latent profile analysis.
23  LC at 3 yr
(1 time)
Biophysics
(1 time)
AIC (1 time)
LC (1 time)
LQLM (1 time)
2012 A modified hypoxia-based TCP model to investigate the clinical outcome of stereotactic hypofractionated regimes for early stage non-small-cell lung cancer (NSCLC).
24  LC3-GFP
(1 time)
Nephrology
(1 time)
GFP (1 time)
LC3-II (1 time)
siRNA (1 time)
2009 Cisplatin-induced macroautophagy occurs prior to apoptosis in proximal tubules in vivo.
25  LC3-K30D, LC3-K51A, or LC3-L53A
(1 time)
Cell Biology
(1 time)
--- 2010 The evolutionarily conserved interaction between LC3 and p62 selectively mediates autophagy-dependent degradation of mutant huntingtin.
26  LC3-phosphatidylethanolamine conjugate
(1 time)
Neurology
(1 time)
BOLD (1 time)
BP (1 time)
DG (1 time)
2017 G-CSF and cognitive dysfunction in elderly diabetic mice with cerebral small vessel disease: Preventive intervention effects and underlying mechanisms.
27  leaf inclination3
(1 time)
Genetics
(1 time)
--- 2018 SPOC domain-containing protein Leaf inclination3 interacts with LIP1 to regulate rice leaf inclination through auxin signaling.
28  level of MAP1LC3
(1 time)
Molecular Biology
(1 time)
BECN1 (1 time)
CRC (1 time)
MAP1LC3A, LC3 (1 time)
2020 Aspirin has a better effect on PIK3CA mutant colorectal cancer cells by PI3K/Akt/Raptor pathway.
29  levels of HMGB1, microtubule-associate protein1light chain3
(1 time)
Medicine
(1 time)
ADM (1 time)
AMPK (1 time)
ELISA (1 time)
2016 [Influence of HMGB1/MAPK/m-TOR signaling pathway on cell autophagy and chemotherapy resistance in K562 cells].
30  levels, including phosphatase and tensin homolog-induced kinase 1, Parkin, MAP1LC3
(1 time)
Translational Medical Research
(1 time)
ATP (1 time)
ChChd3 (1 time)
EA (1 time)
2023 Electroacupuncture ameliorates surgery-induced spatial memory deficits by promoting mitophagy in rats.
31  light 3 chain
(1 time)
Critical Care
(1 time)
miR-30c (1 time)
2020 [Role of hydrogen sulfide mediated autophagy related genes in intestinal function injury of sepsis].
32  light chain 3 fluorescence
(1 time)
Nutritional Sciences
(1 time)
PN (2 times)
BiP (1 time)
CHOP (1 time)
2018 Autophagy May Protect Against Parenteral Nutrition-Associated Liver Disease by Suppressing Endoplasmic Reticulum Stress.
33  light chain 3 subunit
(1 time)
Genetics
(1 time)
MAPs (1 time)
2006 The MAP1 family of microtubule-associated proteins.
34  light chain 3-labeled
(1 time)
Cell Biology
(1 time)
ER (1 time)
LVSs (1 time)
mDAergic (1 time)
2021 Essential role for autophagy protein VMP1 in maintaining neuronal homeostasis and preventing axonal degeneration.
35  light chain 3-related protein-1
(1 time)
Internal Medicine
(1 time)
MAPLC3 (1 time)
PBMCs (1 time)
qPCR (1 time)
2015 [The expression and significance of microtubule-associated protein 1 light chain 3-related protein-1 (LC3) mRNA in peripheral blood mononuclear cells in patients with systemic lupus erythematosus].
36  light chain 3/MAP1LC3
(1 time)
Cell Biology
(1 time)
PE (1 time)
RNA (1 time)
2006 Stimulation of ATG12-ATG5 conjugation by ribonucleic acid.
37  light chain associated protein 3 expression
(1 time)
Neoplasms
(1 time)
MDC (1 time)
2010 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induce autophagic cell death in estrogen receptor negative breast cancer.
38  light chain kinase 3
(1 time)
Virology
(1 time)
ISAV (1 time)
2010 Formation of autophagosomes and redistribution of LC3 upon in vitro infection with infectious salmon anemia virus.
39  light-chain 3 microtubule-associated protein
(1 time)
Pulmonary Medicine
(1 time)
BAL (1 time)
NLRP3 (1 time)
PM (1 time)
2019 Pulmonary inflammation induced by low-dose particulate matter exposure in mice.
40  lipidate MAP1LC3
(1 time)
Virology
(1 time)
CCHFV (1 time)
DUGV (1 time)
2022 The Relationship between DUGBE Virus Infection and Autophagy in Epithelial Cells.
41  little computer 3
(1 time)
Orthopedics
(1 time)
ATG7 (1 time)
BNIP3 (1 time)
ELISA (1 time)
2020 BNIP3 decreases the LPS-induced inflammation and apoptosis of chondrocytes by promoting the development of autophagy.
42  localization of the autophagy marker MAP1LC3B
(1 time)
--- 2018 High content screen for identifying small-molecule LC3B-localization modulators in a renal cancer cell line.
43  longchain protein3
(1 time)
Molecular Biology
(1 time)
AQPs (1 time)
2016 The 'selfish brain' is regulated by aquaporins and autophagy under nutrient deprivation.
44  losses of ATGs such as MAP1LC3B/ATG8F
(1 time)
Cells
(1 time)
ATGs (1 time)
2022 Robustness of the Autophagy Pathway to Somatic Copy Number Losses.
45  lower number of autophagosomes, reduced expression of MAP1LC3
(1 time)
Pharmacology
(1 time)
DKD (1 time)
JAK (1 time)
STAT (1 time)
2021 JAK/STAT pathway promotes the progression of diabetic kidney disease via autophagy in podocytes.
46  microtubule-associated-protein-1-light-chain-3
(1 time)
Microbiology
(1 time)
GBPs (1 time)
IFNG (1 time)
IRGs (1 time)
2017 Viral Replication Complexes Are Targeted by LC3-Guided Interferon-Inducible GTPases.
47  requirements--lateral compression Type 3
(1 time)
Orthopedics
(1 time)
APC1 (1 time)
APC2 (1 time)
LC1 (1 time)
2010 Young-Burgess classification of pelvic ring fractures: does it predict mortality, transfusion requirements, and non-orthopaedic injuries?
48  Tg-GFP-LC3 mice
(1 time)
Medicine
(1 time)
AKI (1 time)
CRP (1 time)
IRI (1 time)
2017 Downregulation of autophagy is associated with severe ischemia-reperfusion-induced acute kidney injury in overexpressing C-reactive protein mice.