| 1 |
NLR family pyrin domain containing 3
(1504 times)
|
Allergy and Immunology
(182 times)
|
IL (242 times)
IL-1beta (208 times)
LPS (157 times)
|
2008 The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1beta secretion but dispensable for adjuvant activity.
|
| 2 |
nucleotide-binding oligomerization domain-like receptor protein 3
(795 times)
|
Pharmacology
(91 times)
|
IL (146 times)
IL-1beta (146 times)
LPS (87 times)
|
2009 Mast cells mediate neutrophil recruitment and vascular leakage through the NLRP3 inflammasome in histamine-independent urticaria.
|
| 3 |
NOD-like receptor protein 3
(652 times)
|
Pharmacology
(98 times)
|
IL-1beta (96 times)
IL (92 times)
ROS (80 times)
|
2009 Dysfunctional inflammasome in Schnitzler's syndrome.
|
| 4 |
NOD-like receptor 3
(114 times)
|
Cell Biology
(15 times)
|
NF-KappaB (26 times)
ROS (20 times)
IL (18 times)
|
2012 Inflammaging: disturbed interplay between autophagy and inflammasomes.
|
| 5 |
NOD-like receptor thermal protein domain associated protein 3
(26 times)
|
Complementary Therapies
(5 times)
|
IL (7 times)
ELISA (6 times)
IL-1beta (5 times)
|
2018 [The effects of methylprednisolone on NLRP3 inflammasome in rats with acute lung injury Induced by Phosgene].
|
| 6 |
domain, leucine rich repeat containing family, pyrin domain containing 3
(5 times)
|
Allergy and Immunology
(2 times)
|
IL-1beta (2 times)
ALD (1 time)
AST (1 time)
|
2010 NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses.
|
| 7 |
NALP3, cryopyrin
(5 times)
|
Science
(2 times)
|
IL (2 times)
ASC (1 time)
HMGB1 (1 time)
|
2009 T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes.
|
| 8 |
nucleotide leukin-rich polypeptide 3
(5 times)
|
Pharmacology
(1 time)
|
HG (2 times)
ROS (2 times)
STZ (2 times)
|
2019 Expression and Contribution of NLRP3 Inflammasome During the Follicular Development Induced by PMSG.
|
| 9 |
NOD-like receptor protein 3 inflammasome
(4 times)
|
Pharmacology
(3 times)
|
alpha-SMA (1 time)
beta-GLU (1 time)
CLP (1 time)
|
2018 Darunavir alleviates irinotecan-induced intestinal toxicity in Vivo.
|
| 10 |
NOD-like receptor thermoprotein domain 3
(4 times)
|
Complementary Therapies
(4 times)
|
ASC (3 times)
ELISA (2 times)
HE (2 times)
|
2021 [Effect of Huangqin Decoction on pyroptosis pathway of NLRP3/caspase-1 in mice with ulcerative colitis].
|
| 11 |
NAcht Leucine-rich repeat Protein 3
(3 times)
|
Nucleic Acids
(1 time)
|
ASC (2 times)
HGFs (2 times)
P. gingivalis-LPS (2 times)
|
2019 Doxycycline inhibits NAcht Leucine-rich repeat Protein 3 inflammasome activation and interleukin-1beta production induced by Porphyromonas gingivalis-lipopolysaccharide and adenosine triphosphate in human gingival fibroblasts.
|
| 12 |
nucleotide-binding domain, leucine-rich repeat, and Pyrin domain 3
(3 times)
|
Eye Diseases
(1 time)
|
AMD (3 times)
ROS (3 times)
RPE (3 times)
|
2021 Effects of Resvega on Inflammasome Activation in Conjunction with Dysfunctional Intracellular Clearance in Retinal Pigment Epithelial (RPE) Cells.
|
| 13 |
oligomerization domain-like receptor, leucine-rich repeat and pyrin domain-containing 3
(3 times)
|
Nutritional Sciences
(2 times)
|
TLR4 (1 time)
WAT (1 time)
|
2017 Fatty Acids and NLRP3 Inflammasome-Mediated Inflammation in Metabolic Tissues.
|
| 14 |
NLR family pyrin domain containing 3 inflammasome
(2 times)
|
Allergy and Immunology
(2 times)
|
3-MA (1 time)
DR (1 time)
IL (1 time)
|
2020 Mycoplasma pneumoniae lipids license TLR-4 for activation of NLRP3 inflammasome and autophagy to evoke a proinflammatory response.
|
| 15 |
NLR protein 3
(2 times)
|
Microbiology
(1 time)
|
NLRC4 (2 times)
ALS (1 time)
ASC (1 time)
|
2018 Expression profile of pattern recognition receptors in skeletal muscle of SOD1(G93A) amyotrophic lateral sclerosis (ALS) mice and sporadic ALS patients.
|
| 16 |
NLR pyrin domain 3
(2 times)
|
Ophthalmology
(1 time)
|
FOXO1 (1 time)
IL-1beta (1 time)
NLRC4 (1 time)
|
2018 miR15a regulates NLRP3 inflammasome proteins in the retinal vasculature.
|
| 17 |
NLR-related protein 3
(2 times)
|
Biochemistry
(1 time)
|
NLR (2 times)
IL (1 time)
NOD (1 time)
|
2011 Inflammasome activation: from inflammatory disease to infection.
|
| 18 |
NLRP3 inflammasome
(2 times)
|
Geriatrics
(1 time)
|
AD (1 time)
ALP (1 time)
BMP (1 time)
|
2021 NLRP3 Inflammasome: A Starring Role in Amyloid-beta- and Tau-Driven Pathological Events in Alzheimer's Disease.
|
| 19 |
Nod-like receptor 3 protein
(2 times)
|
Medicine
(1 time)
|
HE (1 time)
METH (1 time)
TEER (1 time)
|
2019 Methamphetamine Induces Intestinal Inflammatory Injury via Nod-Like Receptor 3 Protein (NLRP3) Inflammasome Overexpression In Vitro and In Vivo.
|
| 20 |
NOD-like receptor family, pyrin domain containing 3 inflammasome
(2 times)
|
Cell Biology
(1 time)
|
DAG (1 time)
FC (1 time)
HFHCD (1 time)
|
2016 Role of Linear Ubiquitination in Health and Disease.
|
| 21 |
NOD-like receptor pyrin-containing receptor 3
(2 times)
|
Cell Biology
(2 times)
|
AMPK (1 time)
CMKLR1 (1 time)
DAMPs (1 time)
|
2021 HOXA9-induced chemerin signals through CMKLR1/AMPK/TXNIP/NLRP3 pathway to induce pyroptosis of trophoblasts and aggravate preeclampsia.
|
| 22 |
nucleotide-binding domain, leucine-rich family, pyrin-containing 3
(2 times)
|
Neoplasms
(2 times)
|
AKT (1 time)
CCK-8 (1 time)
CIK (1 time)
|
2018 NLRP3 in human glioma is correlated with increased WHO grade, and regulates cellular proliferation, apoptosis and metastasis via epithelial-mesenchymal transition and the PTEN/AKT signaling pathway.
|
| 23 |
canonicalnod-like receptor pyrin domain-containing 3
(1 time)
|
Neurosciences
(1 time)
|
PND (1 time)
|
2020 Elamipretide Attenuates Pyroptosis and Perioperative Neurocognitive Disorders in Aged Mice.
|
| 24 |
domain-containing protein-like receptor family, pyrin domain containing protein 3
(1 time)
|
Biochemistry
(1 time)
|
DSS (1 time)
IL (1 time)
SPC (1 time)
|
2016 Soy protein concentrate mitigates markers of colonic inflammation and loss of gut barrier function in vitro and in vivo.
|
| 25 |
miR-96-5p-NLR pyrin domain containing 3
(1 time)
|
Genetics, Medical
(1 time)
|
IL (1 time)
LPS (1 time)
MDA (1 time)
|
2022 USP7-SOX9-miR-96-5p-NLRP3 Network Regulates Myocardial Injury and Cardiomyocyte Pyroptosis in Sepsis.
|
| 26 |
NACHT domain-, leucine-rich repeat-, and pyd-containing protein 3
(1 time)
|
Biochemistry
(1 time)
|
MP (1 time)
MPP (1 time)
NF-kappaB (1 time)
|
2018 Polydatin suppresses the development of lung inflammation and fibrosis by inhibiting activation of the NACHT domain-, leucine-rich repeat-, and pyd-containing protein 3 inflammasome and the nuclear factor-kappaB pathway after Mycoplasma pneumoniae infection.
|
| 27 |
NACHT leucin-rich repeat PYD protein 3
(1 time)
|
Medicine
(1 time)
|
TIR-containing (1 time)
|
2016 Uropathogenic Escherichia coli strain CFT073 disrupts NLRP3 inflammasome activation.
|
| 28 |
NACHT leucin-rich repeat PYD protein 3 inflammasome
(1 time)
|
|
TcpC (1 time)
TLR (1 time)
|
2021 Regulation of Expression of the TIR-Containing Protein C Gene of the Uropathogenic Escherichia coli Strain CFT073.
|
| 29 |
NACHT leucine rich repeat and pyd domains-containing 3
(1 time)
|
Clinical Laboratory Techniques
(1 time)
|
ASC (1 time)
HG (1 time)
IL (1 time)
|
2019 Hydrogen sulfide modulates high glucose-induced NLRP3 inflammasome activation in 3T3-L1 adipocytes.
|
| 30 |
NACHT leucine-rich repeat- and PYD-containing 3
(1 time)
|
Diabetes Mellitus
(1 time)
|
HMGB1 (1 time)
ISO (1 time)
NF-kappaB (1 time)
|
2020 Isomangiferin Attenuates Renal Injury in Diabetic Mice via Inhibiting Inflammation.
|
| 31 |
NASH; however, its mechanism of action involving the pyrin domain-containing-3
(1 time)
|
Chemistry
(1 time)
|
HFSCD (1 time)
MAPK (1 time)
NF-kappaB (1 time)
|
2022 Caffeine Inhibits NLRP3 Inflammasome Activation by Downregulating TLR4/MAPK/NF-kappaB Signaling Pathway in an Experimental NASH Model.
|
| 32 |
NLR family containing protein 3
(1 time)
|
Allergy and Immunology
(1 time)
|
AIM2 (1 time)
CEES (1 time)
Drp1 (1 time)
|
2021 Alterations in Mitochondrial and Inflammasome Homeostasis by 2-Chloroethyl Ethyl Sulfide and Their Mitigation by Curcumin: An in Vitro Study.
|
| 33 |
NLR family, domain of pyrin containing 3
(1 time)
|
Environmental Health
(1 time)
|
CNS (1 time)
KO (1 time)
|
2021 The role of NLRP3 in lead-induced neuroinflammation and possible underlying mechanism.
|
| 34 |
NLR pyrin domain protein 3
(1 time)
|
Natural Science Disciplines
(1 time)
|
CINC (1 time)
IL-18 (1 time)
IL-1beta (1 time)
|
2022 Lutein isolated from Scenedesmus obliquus microalga boosts immunity against cyclophosphamide-induced brain injury in rats.
|
| 35 |
NLR pyrin family domain 3
(1 time)
|
Hematology
(1 time)
|
ATP (1 time)
GVHD (1 time)
IL-1beta (1 time)
|
2019 Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD.
|
| 36 |
NLR-containing protein 3
(1 time)
|
Dentistry
(1 time)
|
IL-1beta (1 time)
NLR (1 time)
|
2015 Activation of inflammasomes in dendritic cells and macrophages by Mycoplasma salivarium.
|
| 37 |
NLR-domain containing receptor 3
(1 time)
|
Allergy and Immunology
(1 time)
|
AKI (1 time)
CS (1 time)
DCD (1 time)
|
2022 Effects of prolonged cold ischemia on the DCD kidney function and Inflammasome expression in rat kidney transplants.
|
| 38 |
NLR-family inflammasome pyrin domain-containing 3
(1 time)
|
Biochemistry
(1 time)
|
CA2 (1 time)
|
2021 A Probe for NLRP3 Inflammasome Inhibitor MCC950 Identifies Carbonic Anhydrase 2 as a Novel Target.
|
| 39 |
NLR-family, leucine-rich repeat protein 3
(1 time)
|
Allergy and Immunology
(1 time)
|
CARDS (1 time)
IL-1beta (1 time)
|
2017 NLRP3 Is a Critical Regulator of Inflammation and Innate Immune Cell Response during Mycoplasma pneumoniae Infection.
|
| 40 |
NLR3-containing a pyrin domain
(1 time)
|
|
AOSD (1 time)
SNPs (1 time)
|
2021 CARD8 SNP rs11672725 Identified as a Potential Genetic Variant for Adult-Onset Still's Disease.
|
| 41 |
NLRP3-knockout mice
(1 time)
|
Neurology
(1 time)
|
HMGB1 (1 time)
TBI (1 time)
|
2021 HMGB1 mediates cognitive impairment caused by the NLRP3 inflammasome in the late stage of traumatic brain injury.
|
| 42 |
NLRP3-siRNA
(1 time)
|
Ophthalmology
(1 time)
|
BC (1 time)
FBC (1 time)
HCECs (1 time)
|
2021 Black Carbon Induces Complement Activation via NLRP3 Inflammasome in Human Corneal Epithelial Cells.
|
| 43 |
NOD protein-like receptor 3
(1 time)
|
Chemistry
(1 time)
|
DSS (1 time)
LPP (1 time)
SCFAs (1 time)
|
2021 Lychee (Litchi chinensis Sonn.) Pulp Phenolics Activate the Short-Chain Fatty Acid-Free Fatty Acid Receptor Anti-inflammatory Pathway by Regulating Microbiota and Mitigate Intestinal Barrier Damage in Dextran Sulfate Sodium-Induced Colitis in Mice.
|
| 44 |
Nod-like receptor pyrin containing 3 inflammasome
(1 time)
|
Allergy and Immunology
(1 time)
|
IL-18 (1 time)
IL-1beta (1 time)
MDD (1 time)
|
2017 NLRP3 inflammasome-driven pathways in depression: Clinical and preclinical findings.
|
| 45 |
nonobese diabetic-like receptor family pyrin domain containing 3
(1 time)
|
Pathology
(1 time)
|
TXNIP (1 time)
|
2020 Knockdown of Long Noncoding RNAs of Maternally Expressed 3 Alleviates Hyperoxia-Induced Lung Injury via Inhibiting Thioredoxin-Interacting Protein-Mediated Pyroptosis by Binding to miR-18a.
|
| 46 |
Notably, the pyrin domain containing 3
(1 time)
|
|
CNS (1 time)
SCI (1 time)
TBI (1 time)
|
2022 TI: NLRP3 Inflammasome-Dependent Pyroptosis in CNS Trauma: A Potential Therapeutic Target.
|
| 47 |
nucleotide binding to the oligonucleotide receptor protein 3
(1 time)
|
Nervous System Physiological Phenomena
(1 time)
|
STAT3 (1 time)
|
2018 Downregulation of signal transduction and STAT3 expression exacerbates oxidative stress mediated by NLRP3 inflammasome.
|
| 48 |
nucleotide receptor protein 3
(1 time)
|
Biology
(1 time)
|
FXII (1 time)
IL-1beta (1 time)
|
2020 Cold-induced urticarial autoinflammatory syndrome related to factor XII activation.
|
| 49 |
nucleotide-binding leucine-rich repeat-containing pyrin receptor 3
(1 time)
|
Biochemistry
(1 time)
|
FMF (1 time)
MEFV (1 time)
|
2012 Reduced expression of NLRP3 and MEFV in human ischemic heart tissue.
|
| 50 |
proteins leucine-rich repeat protein 3
(1 time)
|
Neurology
(1 time)
|
ASC (1 time)
OPCs (1 time)
SCI (1 time)
|
2019 The relationship between inflammasomes and the endoplasmic reticulum stress response in the injured spinal cord.
|
| 51 |
sensor leucine-rich-containing family, pyrin domain containing 3
(1 time)
|
Endocrinology
(1 time)
|
IL (1 time)
SAT (1 time)
VAT (1 time)
|
2016 A Role of the Inflammasome in the Low Storage Capacity of the Abdominal Subcutaneous Adipose Tissue in Obese Adolescents.
|
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