1 |
platelet-derived growth factor receptor alpha
(489 times)
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Neoplasms (168 times)
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GISTs (142 times) GIST (104 times) SDH (20 times)
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1990 The human PDGF receptor alpha-subunit gene maps to chromosome 4 in close proximity to c-kit.
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2 |
PDGF receptor-alpha
(7 times)
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Neoplasms (5 times)
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GIST (3 times) IGF-1R (2 times) AM (1 time)
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2004 Biology of gastrointestinal stromal tumors.
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3 |
PDGFRalpha
(4 times)
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Molecular Biology (1 time)
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FIP1L1 (2 times) Asp816Val (1 time) CML (1 time)
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2003 A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome.
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4 |
PDGF-alpha receptor
(2 times)
|
Biochemistry (1 time)
|
PDGF (2 times) PI3K (1 time)
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2006 PI3-kinase/Akt-dependent antiapoptotic signaling by the PDGF alpha receptor is negatively regulated by Src family kinases.
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5 |
PDGF receptor, alpha polypeptide
(1 time)
|
Molecular Biology (1 time)
|
BRET (1 time) EGFR (1 time) GIST (1 time)
|
2007 Monitoring interactions between receptor tyrosine kinases and their downstream effector proteins in living cells using bioluminescence resonance energy transfer.
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6 |
PDGF system components, particularly the alpha subtype receptor
(1 time)
|
Neurology (1 time)
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FISH (1 time) PDGF (1 time)
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2000 Amplification of the platelet-derived growth factor receptor-A (PDGFRA) gene occurs in oligodendrogliomas with grade IV anaplastic features.
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