| 1 |
phosphatase and tensin homolog
(2610 times)
|
Neoplasms
(638 times)
|
PI3K (362 times)
mTOR (178 times)
miRNAs (116 times)
|
1998 Inherited macrocephaly-hamartoma syndromes.
|
| 2 |
phosphatase and tensin homolog deleted on chromosome ten
(421 times)
|
Neoplasms
(77 times)
|
PI3K (71 times)
mTOR (23 times)
qRT-PCR (20 times)
|
1998 Denaturing high performance liquid chromatography (DHPLC) used in the detection of germline and somatic mutations.
|
| 3 |
phosphatase and tensin homolog tumor suppressor gene
(6 times)
|
Neoplasms
(4 times)
|
PI3K (3 times)
mTOR (2 times)
CCND1 (1 time)
|
2002 CCND1- and ERBB2-gene deregulation and PTEN mutation analyses in invasive lobular carcinoma of the breast.
|
| 4 |
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
(4 times)
|
Cell Biology
(1 time)
|
AEII (1 time)
EcR-B1 (1 time)
EMT (1 time)
|
2009 PTEN contributes to profound PI3K/Akt signaling pathway deregulation in dystrophin-deficient dog muscle.
|
| 5 |
protein tyrosine phosphatase
(3 times)
|
Obstetrics
(1 time)
|
HNSCC (1 time)
LCR (1 time)
miR-139-5p (1 time)
|
2013 Estimate of the accelerated proliferation by protein tyrosine phosphatase (PTEN) over expression in postoperative radiotherapy of head and neck squamous cell carcinoma.
|
| 6 |
protein tyrosine phosphatase gene
(3 times)
|
Pharmacology
(1 time)
|
CASC2 (1 time)
EGFR (1 time)
miRNA (1 time)
|
2014 [Expression and significance of PTEN, P-ERK and P-AKT in the middle ear cholesteatoma].
|
| 7 |
phosphatase homologous to tensin
(2 times)
|
Neoplasms
(1 time)
|
BMPs (1 time)
EGFR (1 time)
SHIP2 (1 time)
|
2007 Phosphoinositol phosphatase SHIP2 promotes cancer development and metastasis coupled with alterations in EGF receptor turnover.
|
| 8 |
phosphatase with sequence homology to tensin
(2 times)
|
Science
(1 time)
|
NO (1 time)
|
2011 On-off system for PI3-kinase-Akt signaling through S-nitrosylation of phosphatase with sequence homology to tensin (PTEN).
|
| 9 |
probably existed after adjusted for confounding factors
(2 times)
|
Communicable Diseases
(1 time)
|
AL (1 time)
API (1 time)
MSP (1 time)
|
2016 [Chemical exposure, leukemia related DNA methylation changes and childhood acute leukemia].
|
| 10 |
PTEN/MMAC/TEP
(2 times)
|
Neoplasms
(1 time)
|
AR (1 time)
|
2001 Mutation of the PTEN gene in advanced cervical cancer correlated with tumor progression and poor outcome after radiotherapy.
|
| 11 |
ten protein
(2 times)
|
Medicine
(1 time)
|
HCC (1 time)
MsrA (1 time)
ROS (1 time)
|
2007 Relationship between PTEN and VEGF expression and clinicopathological characteristics in HCC.
|
| 12 |
P-phosphatase and TENsin
(1 time)
|
Neoplasms
(1 time)
|
HPV (1 time)
NFV (1 time)
|
2009 Radiation response in two HPV-infected head-and-neck cancer cell lines in comparison to a non-HPV-infected cell line and relationship to signaling through AKT.
|
| 13 |
phosphatase and tensin-homolog as inhibitor
(1 time)
|
Neoplasms
(1 time)
|
PI3K (1 time)
PIK3CA (1 time)
|
2019 PIK3CA and PTEN Genes Expressions in Breast Cancer.
|
| 14 |
phosphatase gene
(1 time)
|
Gastroenterology
(1 time)
|
CRC (1 time)
miR-21 (1 time)
PI3K (1 time)
|
2016 MicroRNA-21 promotes phosphatase gene and protein kinase B/phosphatidylinositol 3-kinase expression in colorectal cancer.
|
| 15 |
phosphatase homolog/tensin homolog
(1 time)
|
Biochemistry
(1 time)
|
DLC1 (1 time)
ECM (1 time)
F-actin (1 time)
|
2014 Molecular physiology of the tensin brotherhood of integrin adaptor proteins.
|
| 16 |
phosphatase tension homolog deletion
(1 time)
|
Cell Biology
(1 time)
|
hPDLSCs (1 time)
PDL (1 time)
|
2020 Osteocyte-derived exosomes induced by mechanical strain promote human periodontal ligament stem cell proliferation and osteogenic differentiation via the miR-181b-5p/PTEN/AKT signaling pathway.
|
| 17 |
phosphatidylinositol-3-phosphatase
(1 time)
|
Cell Biology
(1 time)
|
ELA (1 time)
mTOR (1 time)
TauT (1 time)
|
2014 mTOR ensures increased release and reduced uptake of the organic osmolyte taurine under hypoosmotic conditions in mouse fibroblasts.
|
| 18 |
Phospho tensin gene
(1 time)
|
Microbiology
(1 time)
|
---
|
2011 Immunohistochemical phospho tensin tumor suppressor gene staining patterns in endometrial hyperplasias: a 2-year study.
|
| 19 |
phosphoinositide-3-phosphatase
(1 time)
|
Cardiology
(1 time)
|
Ca,L (1 time)
DN-p110alpha (1 time)
IGF-1 (1 time)
|
2006 Insulin-like growth factor-1 and PTEN deletion enhance cardiac L-type Ca2+ currents via increased PI3Kalpha/PKB signaling.
|
| 20 |
phosphotensin
(1 time)
|
Toxicology
(1 time)
|
BBN (1 time)
BW (1 time)
DIM (1 time)
|
2015 Antiproliferative and anti-inflammatory properties of diindolylmethane and lupeol against N-butyl-N-(4-hydroxybutyl) nitrosamine induced bladder carcinogenesis in experimental rats.
|
| 21 |
plasmid as a tumor suppressor gene
(1 time)
|
General Surgery
(1 time)
|
BPEI (1 time)
PCI (1 time)
PS (1 time)
|
2012 Glioma cell growth inhibition following photochemical internalization enhanced non-viral PTEN gene transfection.
|
| 22 |
positively with expression of p-S6and p-4EBP1
(1 time)
|
Neoplasms
(1 time)
|
---
|
2012 PTEN promoter methylation and activation of the PI3K/Akt/mTOR pathway in pediatric gliomas and influence on clinical outcome.
|
| 23 |
pre-existing phosphatase and tensin homolog
(1 time)
|
Neoplasms
(1 time)
|
ERG (1 time)
mTOR (1 time)
|
2012 Loss of pSer2448-mTOR expression is linked to adverse prognosis and tumor progression in ERG-fusion-positive cancers.
|
| 24 |
proliferation
(1 time)
|
Endocrinology
(1 time)
|
ATCs (1 time)
CDK (1 time)
PDTCs (1 time)
|
2014 Cell cycle deregulation and TP53 and RAS mutations are major events in poorly differentiated and undifferentiated thyroid carcinomas.
|
| 25 |
protein homologue
(1 time)
|
General Surgery
(1 time)
|
miR-221 (1 time)
|
2019 [Changes in expression of microRNA-221 and phosphatase and tension protein homologue in nerve stump after peripheral nerve injury].
|
| 26 |
protein product
(1 time)
|
Science
(1 time)
|
---
|
1999 Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway.
|
| 27 |
PTEN holes
(1 time)
|
Biophysics
(1 time)
|
---
|
2012 PIP3 waves and PTEN dynamics in the emergence of cell polarity.
|
| 28 |
PTEN M-Neg
(1 time)
|
Allergy and Immunology
(1 time)
|
CD (1 time)
HLA (1 time)
IFN (1 time)
|
2011 Enhanced lymphocyte interferon (IFN)-gamma responses in a PTEN mutation-negative Cowden disease kindred.
|
| 29 |
PTEN mutant associated with Cowden's disease
(1 time)
|
Science
(1 time)
|
---
|
1999 Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway.
|
| 30 |
PTEN product protein
(1 time)
|
Neoplasms
(1 time)
|
AJCC (1 time)
|
2002 Expression and prognostic significance of PTEN product protein in patients with esophageal squamous cell carcinoma.
|
| 31 |
PTEN protein
(1 time)
|
Cell Biology
(1 time)
|
---
|
2000 Phosphorylation of the PTEN tail regulates protein stability and function.
|
| 32 |
PTEN-del
(1 time)
|
Science
(1 time)
|
PCa (1 time)
PSA (1 time)
|
2020 TIP5 primes prostate luminal cells for the oncogenic transformation mediated by PTEN-loss.
|
| 33 |
PTEN-LONG, or PTEN-L
(1 time)
|
Genetics, Medical
(1 time)
|
GAS1 (1 time)
GDNF (1 time)
|
2018 Additive effects of the combined expression of soluble forms of GAS1 and PTEN inhibiting glioblastoma growth.
|
| 34 |
PTEN-positive
(1 time)
|
Neoplasms
(1 time)
|
DFS (1 time)
HER2 (1 time)
HRs (1 time)
|
2013 Impact of PTEN protein expression on benefit from adjuvant trastuzumab in early-stage human epidermal growth factor receptor 2-positive breast cancer in the North Central Cancer Treatment Group N9831 trial.
|
| 35 |
PTEN-RNAi
(1 time)
|
Biochemistry
(1 time)
|
AIA (1 time)
FLSs (1 time)
RA (1 time)
|
2019 Over-Expression of PTEN Suppresses the Proliferation and Migration of Fibroblast-Like Synoviocytes in Adjuvant-Induced Arthritis.
|
| 36 |
PTENsi-GFP
(1 time)
|
Neurology
(1 time)
|
GFP (1 time)
gp120 (1 time)
siRNA (1 time)
|
2011 PTEN gene silencing prevents HIV-1 gp120(IIIB)-induced degeneration of striatal neurons.
|
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