| 1 |
intrathecal
(2180 times)
|
Neurology
(640 times)
|
i.c.v (247 times)
i.p (117 times)
CNS (116 times)
|
1975 Leukoencephalopathy following combined therapy of central nervous system leukemia and lymphoma.
|
| 2 |
intratracheal
(606 times)
|
Pharmacology
(94 times)
|
i.p (81 times)
BAL (68 times)
LPS (64 times)
|
1973 Immunization of mice with live attenuated encephalomyocarditis virus: local immunity and survival.
|
| 3 |
intratumoral
(350 times)
|
Neoplasms
(165 times)
|
i.v (38 times)
s.c (31 times)
i.p (28 times)
|
1977 [Host-tumour relationships and immediate hypersensitivity reactions].
|
| 4 |
injection
(58 times)
|
Neurology
(10 times)
|
i.p (5 times)
DRG (4 times)
CFA (3 times)
|
1988 Endoscopic intratumoral injection of OK-432 and Langerhans' cells in patients with gastric carcinoma.
|
| 5 |
intrathoracic
(26 times)
|
Pharmacology
(9 times)
|
LPS (5 times)
i.p (3 times)
PAF (3 times)
|
1982 Sensitivity to carbon dioxide in mosquitoes infected with California serogroup arboviruses.
|
| 6 |
intratumor
(18 times)
|
Pharmacology
(3 times)
|
i.v (7 times)
i.p (2 times)
MVD (2 times)
|
1978 Mouse-strain difference in immunoprophylactic and immunotherapeutic effects of BCG on carcinogen-induced autochthonous tumors.
|
| 7 |
investigated the effect of intrathecal
(14 times)
|
Neurology
(4 times)
|
CNS (2 times)
i.pl (2 times)
NMDA (2 times)
|
1990 Intrathecal N-methyl-D-aspartate induces hyperexcitability in rat dorsal horn convergent neurones.
|
| 8 |
intratibially
(8 times)
|
Neoplasms
(3 times)
|
IC (3 times)
PCa (3 times)
s.c (3 times)
|
1984 Effects of disodium etidronate in murine tumor models.
|
| 9 |
injected
(6 times)
|
Obstetrics
(1 time)
|
ACA (1 time)
alpha-SMA (1 time)
AMF (1 time)
|
1999 Adenovirus-mediated tissue-targeted expression of the HSVtk gene for the treatment of breast cancer.
|
| 10 |
instilled
(6 times)
|
Pharmacology
(2 times)
|
DEP (3 times)
ALI (2 times)
MPO (2 times)
|
1995 The pulmonary absorption of aerosolized and intratracheally instilled rhG-CSF and monoPEGylated rhG-CSF.
|
| 11 |
indicate that intrathecal
(5 times)
|
Neoplasms
(3 times)
|
APCs (1 time)
COX (1 time)
DC (1 time)
|
1997 Spinal strychnine alters response properties of nociceptive-specific neurons in rat medial thalamus.
|
| 12 |
intrathoracically
(5 times)
|
Tropical Medicine
(2 times)
|
WT (2 times)
YF (2 times)
DEN (1 time)
|
1988 Comparison of intrapulmonary, percutaneous intrathoracic, and subcutaneous models for the propagation of human pulmonary and nonpulmonary cancer cell lines in athymic nude mice.
|
| 13 |
inoculation
(4 times)
|
Cell Biology
(2 times)
|
BSC (1 time)
i.n (1 time)
PLA (1 time)
|
2009 Activation of complement in the discordant heart xenotransplantation of pig-to-monkey model and the impact of intrathymic inoculation of xenogeneic antigen combined with whole-body gamma-radiation.
|
| 14 |
into the intrathecal
(4 times)
|
Pharmacology
(3 times)
|
HR (2 times)
BBB (1 time)
DTPA (1 time)
|
1990 Rostrocaudal localization of cardiovascular responses induced by intrathecal administration of apomorphine in conscious, freely moving rats.
|
| 15 |
intrathecal administration
(4 times)
|
Physiology
(2 times)
|
AA (1 time)
Dyn (1 time)
i.p (1 time)
|
1997 [Effects of dynorphin A1-17 on the activities, immunoreactivities and mRNA expression of cNOS and iNOS in rat spinal cord and their mechanisms].
|
| 16 |
intrathymically
(4 times)
|
Allergy and Immunology
(2 times)
|
AChR (1 time)
ALS (1 time)
APC (1 time)
|
1982 High- and low-leukemogenic variants of the radiation leukemia virus (RadLV) differ in ability to induce tumor-specific immune suppression.
|
| 17 |
into the spinal lumbar intrathecal
(3 times)
|
Pharmacology
(2 times)
|
NO (2 times)
L-NAME (1 time)
NMDA (1 time)
|
1994 Inhibition of clonic seizure-like excitatory effects induced by intrathecal morphine using two NMDA receptor antagonists: MK-801 and ACEA-1011.
|
| 18 |
CuO-injected
(2 times)
|
Toxicology
(1 time)
|
BAL (1 time)
CuO (1 time)
MT (1 time)
|
1993 Pulmonary clearance and toxicity of intratracheally instilled cupric oxide in rats.
|
| 19 |
into the spinal intrathecal
(2 times)
|
Pharmacology
(1 time)
|
---
|
1987 Spinal cord mediation of the opioid analgesia of pregnancy.
|
| 20 |
intrathecal application
(2 times)
|
Pharmacology
(1 time)
|
A-URS (1 time)
AMPA (1 time)
S-LPP (1 time)
|
1997 BU-224 produces spinal antinociception as an agonist at imidazoline I2 receptors.
|
| 21 |
intratumorous
(2 times)
|
Pharmacology
(1 time)
|
i.p (2 times)
ACR (1 time)
ER (1 time)
|
1987 Antitumor effect of polysaccharide grifolan NMF-5N on syngeneic tumor in mice.
|
| 22 |
investigate the intrathecal
(2 times)
|
Neurology
(1 time)
|
CCI (1 time)
MAP (1 time)
NO (1 time)
|
1997 Adenosine receptor activation suppresses tactile hypersensitivity and potentiates spinal cord stimulation in mononeuropathic rats.
|
| 23 |
test, intrathecal
(2 times)
|
Neurology
(2 times)
|
BYG-Bz (1 time)
CI (1 time)
NMDA (1 time)
|
2003 Powerful antinociceptive effects of the cone snail venom-derived subtype-selective NMDA receptor antagonists conantokins G and T.
|
| 24 |
administration-intrathecal
(1 time)
|
Neurology
(1 time)
|
i.v (1 time)
s.c (1 time)
|
2020 Targeting Therapeutic Antibodies to the CNS: a Comparative Study of Intrathecal, Intravenous, and Subcutaneous Anti-Nogo A Antibody Treatment after Stroke in Rats.
|
| 25 |
co-injection
(1 time)
|
Neurology
(1 time)
|
NMDA (1 time)
RTX (1 time)
TRPA1 (1 time)
|
2012 Involvement of the glutamatergic system in the nociception induced intrathecally for a TRPA1 agonist in rats.
|
| 26 |
i.c.v. trazodone (P<0.01), while WAY-100635
(1 time)
|
Psychopharmacology
(1 time)
|
i.c.v (1 time)
|
2004 Intracerebroventricular injection of trazodone produces 5-HT receptor subtype mediated anti-nociception at the supraspinal and spinal levels.
|
| 27 |
i.t. blocked SP
(1 time)
|
Drug Therapy
(1 time)
|
i.pl (2 times)
N/OFQ (1 time)
NOR (1 time)
|
1999 Dose-related opposite modulation by nociceptin/orphanin FQ of substance P nociception in the nociceptors and spinal cord.
|
| 28 |
identical for adenosine agonist
(1 time)
|
Pharmacology
(1 time)
|
CADO (1 time)
i.c.v (1 time)
NBI (1 time)
|
1987 Involvement of A2 adenosine receptors in spinal mechanisms of antinociception.
|
| 29 |
identify that intrathecal
(1 time)
|
Medicine
(1 time)
|
CFA (1 time)
DEX (1 time)
Fos-ir (1 time)
|
2014 Inhibiting spinal neuron-astrocytic activation correlates with synergistic analgesia of dexmedetomidine and ropivacaine.
|
| 30 |
if the intrathecally-administered
(1 time)
|
Biochemistry
(1 time)
|
3A5P (1 time)
VPM (1 time)
|
1992 Analgesic effects of intrathecally-administered 3 alpha-hydroxy-5 alpha-pregnan-20-one in a rat mechanical visceral pain model.
|
| 31 |
if they are administered intrathecally
(1 time)
|
Biomedical Engineering
(1 time)
|
BI (1 time)
BP (1 time)
CNS (1 time)
|
2003 Antinociceptive effects of hydromorphone, bupivacaine and biphalin released from PLGA polymer after intrathecal implantation in rats.
|
| 32 |
Importantly, the intratracheal
(1 time)
|
Allergy and Immunology
(1 time)
|
IFN (1 time)
NK (1 time)
|
2005 IP-10 mediates selective mononuclear cell accumulation and activation in response to intrapulmonary transgenic expression and during adenovirus-induced pulmonary inflammation.
|
| 33 |
improve the intracerebral and intratumoral
(1 time)
|
Neoplasms
(1 time)
|
CED (1 time)
EGF (1 time)
EGFR (1 time)
|
2002 Convection-enhanced delivery of boronated epidermal growth factor for molecular targeting of EGF receptor-positive gliomas.
|
| 34 |
including the direct intratumoral
(1 time)
|
Neoplasms
(1 time)
|
CEA (1 time)
ICAM-1 (1 time)
LFA-3 (1 time)
|
2005 Induction of an antigen cascade by diversified subcutaneous/intratumoral vaccination is associated with antitumor responses.
|
| 35 |
induce antinociception when administered
(1 time)
|
Pharmacology
(1 time)
|
EHNA (1 time)
|
1994 Adenosine kinase and adenosine deaminase inhibition modulate spinal adenosine- and opioid agonist-induced antinociception in mice.
|
| 36 |
induced by selected opioids
(1 time)
|
Pharmacology
(1 time)
|
EHNA (1 time)
|
1994 Adenosine kinase and adenosine deaminase inhibition modulate spinal adenosine- and opioid agonist-induced antinociception in mice.
|
| 37 |
induced by serotonin
(1 time)
|
Neurology
(1 time)
|
---
|
1987 Interdependence of spinal adenosinergic, serotonergic and noradrenergic systems mediating antinociception.
|
| 38 |
induced by substance P
(1 time)
|
Drug Therapy
(1 time)
|
N/OFQ (1 time)
|
2003 In vivo pain-inhibitory role of nociceptin/orphanin FQ in spinal cord.
|
| 39 |
induction of behaviors by SP
(1 time)
|
Drug Therapy
(1 time)
|
SP (2 times)
GABAB (1 time)
|
1989 Baclofen, gamma-aminobutyric acidB receptors and substance P in the mouse spinal cord.
|
| 40 |
inhibitor S3I-201
(1 time)
|
Neurology
(1 time)
|
DRG (1 time)
LDH (1 time)
|
2017 Activation of the RAGE/STAT3 Pathway in the Dorsal Root Ganglion Contributes to the Persistent Pain Hypersensitivity Induced by Lumbar Disc Herniation.
|
| 41 |
inhibitor, and mCPP
(1 time)
|
Neurology
(1 time)
|
A-URS (1 time)
AMPA (1 time)
S-LPP (1 time)
|
2014 Roles of the spinal glutamatergic pathway activated through alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptors and its interactions with spinal noradrenergic and serotonergic pathways in the rat urethral continence mechanisms.
|
| 42 |
injected through indwelling intrathecal
(1 time)
|
Drug Therapy
(1 time)
|
Dyn A (1 time)
|
1988 Neurological dysfunction after intrathecal injection of dynorphin A (1-13) in the rat. I. Injection procedures modify pharmacological responses.
|
| 43 |
Injection of calcium
(1 time)
|
Drug Therapy
(1 time)
|
PPQ (1 time)
|
1992 A proposed mechanism of action for the antinociceptive effect of intrathecally administered calcium in the mouse.
|
| 44 |
injection test, intrathecal
(1 time)
|
Brain
(1 time)
|
---
|
2001 Antinociceptive profiles of aspirin and acetaminophen in formalin, substance P and glutamate pain models.
|
| 45 |
injury, the intrathecal
(1 time)
|
Physiology
(1 time)
|
4-DAMP (1 time)
EA (1 time)
|
2009 Spinal cholinergic mechanism of the relieving effects of electroacupuncture on cold and warm allodynia in a rat model of neuropathic pain.
|
| 46 |
insensitivity to intrathecal
(1 time)
|
Neurology
(1 time)
|
PSL (1 time)
|
2005 Pretreatment with antiserum against dynorphin, substance P, or cholecystokinin enhances the morphine-produced anti-allodynia in the sciatic nerve ligated mice.
|
| 47 |
instilled via the trachea
(1 time)
|
Toxicology
(1 time)
|
BAL (1 time)
CB (1 time)
COPD (1 time)
|
2003 Ultrafine carbon black particles enhance respiratory syncytial virus-induced airway reactivity, pulmonary inflammation, and chemokine expression.
|
| 48 |
intention to be used intrathecally
(1 time)
|
Anesthesiology
(1 time)
|
SCBF (1 time)
|
1999 Sameridine--intrathecal injection in the rat. Morphometric and morphologic analysis after chronic administration and effects on spinal cord blood flow.
|
| 49 |
Interactions of adenosine agonists
(1 time)
|
Pharmacology
(1 time)
|
CADO (1 time)
i.c.v (1 time)
NBI (1 time)
|
1987 Involvement of A2 adenosine receptors in spinal mechanisms of antinociception.
|
| 50 |
into the right thoracic cavity
(1 time)
|
Neoplasms
(1 time)
|
LN (1 time)
VEGFs (1 time)
|
2004 Enhancement of pleural dissemination and lymph node metastasis of intrathoracic lung cancer cells by vascular endothelial growth factors (VEGFs).
|
| 51 |
into the spinal subarachnoid space
(1 time)
|
Neurology
(1 time)
|
LAM (1 time)
OVA (1 time)
SCG (1 time)
|
2003 Acute down-regulation of antibody production following spinal cord injury: role of systemic catecholamines.
|
| 52 |
intra-tonsillar
(1 time)
|
Allergy and Immunology
(1 time)
|
ASC (1 time)
i.n (1 time)
IgG (1 time)
|
1995 Induction of compartmentalized B-cell responses in human tonsils.
|
| 53 |
Intra-tumoral
(1 time)
|
Neoplasms
(1 time)
|
Ab (1 time)
AdV (1 time)
GM-CSF (1 time)
|
2015 Immunotherapeutic intervention with oncolytic adenovirus in mouse mammary tumors.
|
| 54 |
intracisternal
(1 time)
|
Pharmacology
(1 time)
|
PLH (1 time)
|
2011 SCH23390, a dopamine D1 receptor antagonist, suppressed scratching behavior induced by compound 48/80 in mice.
|
| 55 |
Intrathalamic
(1 time)
|
Virology
(1 time)
|
IM (1 time)
p.i (1 time)
|
1984 Nasal and intrathalamic inoculations of primates with Tacaribe virus: protection against Argentine hemorrhagic fever and absence of neurovirulence.
|
| 56 |
intrathecal routes
(1 time)
|
Pharmacology
(1 time)
|
i.c.v (1 time)
|
1994 Peripheral kappa-opioid receptors mediate the antinociceptive effect of fedotozine (correction of fetodozine) on the duodenal pain reflex inrat.
|
| 57 |
intrathecal subarachnoid space
(1 time)
|
Brain
(1 time)
|
i.c.v (1 time)
IA (1 time)
|
1985 Supraspinal and spinal mediation of naloxone-induced morphine withdrawal in rats.
|
| 58 |
intrathecally administered
(1 time)
|
Brain
(1 time)
|
TF (1 time)
|
1997 Involvement of endogenous opioids and ATP-sensitive potassium channels in the mediation of carbachol-induced antinociception at the spinal level: a behavioral study in rats.
|
| 59 |
intrathoracic cavity
(1 time)
|
Allergy and Immunology
(1 time)
|
AFC (1 time)
HRBC (1 time)
i.p (1 time)
|
1989 Antibody responses in the liver and bile of rats injected with horse erythrocytes.
|
| 60 |
intratracheal bolus
(1 time)
|
Toxicology
(1 time)
|
cAMP (1 time)
ISO (1 time)
ISO i.t (1 time)
|
1998 Post-exposure treatment with isoproterenol attenuates pulmonary edema in phosgene-exposed rabbits.
|
| 61 |
intratracheal treatment
(1 time)
|
Pharmacology
(1 time)
|
ACEIs (1 time)
B2 receptor (1 time)
DABK (1 time)
|
2021 The role of TRPA1 and TRPV4 channels in bronchoconstriction and plasma extravasation in airways of rats treated with captopril.
|
| 62 |
intratracheally dosed
(1 time)
|
Pharmacology
(1 time)
|
BAL (1 time)
ROFA (1 time)
|
2007 Soluble metals in residual oil fly ash alter innate and adaptive pulmonary immune responses to bacterial infection in rats.
|
| 63 |
intratrail
(1 time)
|
Allergy and Immunology
(1 time)
|
Ab (1 time)
HRBC (1 time)
i.v (1 time)
|
1986 Influence of a minor recurrent idiotype on the regulation of immune response: route dependence.
|
| 64 |
intratumor administration
(1 time)
|
Neoplasms
(1 time)
|
---
|
1995 Evaluation of biometric parameters of Morris hepatoma after application of human recombinant tumor necrosis factor.
|
| 65 |
intratumoral pathway
(1 time)
|
Biocompatible Materials
(1 time)
|
DOX (1 time)
i.v (1 time)
PB (1 time)
|
2016 Nano-rods of doxorubicin with poly(l-glutamic acid) as a carrier-free formulation for intratumoral cancer treatment.
|
| 66 |
Intratumoural
(1 time)
|
Neoplasms
(1 time)
|
FdUrd (1 time)
i.v (1 time)
IdUrd (1 time)
|
2004 Highly efficient DNA incorporation of intratumourally injected [125I]iododeoxyuridine under thymidine synthesis blocking in human glioblastoma xenografts.
|
| 67 |
isoproterenol
(1 time)
|
Drug Therapy
(1 time)
|
---
|
1988 Micturition in the unanesthetized rat: spinal vs. peripheral pharmacology of the adrenergic system.
|
| 68 |
tested in substance P
(1 time)
|
Pharmacology
(1 time)
|
---
|
2003 Antinociceptive effects of methysergide in various pain models.
|
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