| 1 |
N6-methyladenosine
(1402 times)
|
Neoplasms
(222 times)
|
METTL3 (96 times)
FTO (77 times)
mRNA (62 times)
|
1976 5'-Terminal and internal methylated nucleotide sequences in HeLa cell mRNA.
|
| 2 |
N6-methylation of adenosine
(18 times)
|
Neoplasms
(4 times)
|
GSEA (2 times)
ROC (2 times)
YTH (2 times)
|
2015 N6-adenosine methylation in MiRNAs.
|
| 3 |
Methylation at the N6 position of adenosine
(14 times)
|
Microbiology
(2 times)
|
HA (2 times)
CLIP (1 time)
ds (1 time)
|
2017 Viral Epitranscriptomics.
|
| 4 |
modification is N6-methyladenosine
(13 times)
|
Cell Biology
(2 times)
|
DNA (1 time)
FDmMGenes (1 time)
LASSO (1 time)
|
2017 Detecting N6-methyladenosine sites from RNA transcriptomes using ensemble Support Vector Machines.
|
| 5 |
mRNAs, N6-methyladenosine
(6 times)
|
Biochemistry
(2 times)
|
BioID (1 time)
KRT7 (1 time)
MAGE (1 time)
|
2018 The m6A Writer: Rise of a Machine for Growing Tasks.
|
| 6 |
methylation of adenosine at the N6-position
(4 times)
|
Chemistry
(1 time)
|
m1A (1 time)
mRNA (1 time)
RNA MTases (1 time)
|
2019 m6A-mRNA methylation regulates cardiac gene expression and cellular growth.
|
| 7 |
methyl groups at the N6 position
(3 times)
|
Botany
(1 time)
|
8-NO2-G (1 time)
CTD (1 time)
m5C (1 time)
|
2018 Addition of m6A to SV40 late mRNAs enhances viral structural gene expression and replication.
|
| 8 |
N6-methylated adenine
(3 times)
|
Biochemistry
(2 times)
|
N6-mAMP (1 time)
|
2018 m6A RNA Degradation Products Are Catabolized by an Evolutionarily Conserved N6-Methyl-AMP Deaminase in Plant and Mammalian Cells.
|
| 9 |
m2G and N6-methyladenosine
(2 times)
|
Bacteriology
(1 time)
|
m1A (1 time)
m2G (1 time)
m6G (1 time)
|
1979 23S ribosomal ribonucleic acid of macrolide-producing streptomycetes contains methylated adenine.
|
| 10 |
methyl-6-adenosine
(2 times)
|
Biochemistry
(1 time)
|
5mC (1 time)
LINE (1 time)
m5C (1 time)
|
2017 Illustrating the Epitranscriptome at Nucleotide Resolution Using Methylation-iCLIP (miCLIP).
|
| 11 |
Methylation of the adenosine base at the nitrogen-6 position
(2 times)
|
Molecular Biology
(2 times)
|
ABEs (1 time)
SNP (1 time)
|
2017 Most m6A RNA Modifications in Protein-Coding Regions Are Evolutionarily Unconserved and Likely Nonfunctional.
|
| 12 |
modification in eukaryotic cells, N 6-methyladenosine
(2 times)
|
Cell Biology
(1 time)
|
KSHV (1 time)
SV40 (1 time)
|
2018 The RNA Epitranscriptome of DNA Viruses.
|
| 13 |
modifiers are N6-methyladenosine
(2 times)
|
Medicine
(1 time)
|
IGF2BP2 (1 time)
KD (1 time)
KO (1 time)
|
2019 IGF2BP2 regulates DANCR by serving as an N6-methyladenosine reader.
|
| 14 |
mRNA and noncoding RNAs is N6-methyladenosine
(2 times)
|
Toxicology
(1 time)
|
GC (1 time)
GSEA (1 time)
MeRIP-seq (1 time)
|
2019 Reduced m6A modification predicts malignant phenotypes and augmented Wnt/PI3K-Akt signaling in gastric cancer.
|
| 15 |
6-methylaminopurine
(1 time)
|
Biochemistry
(1 time)
|
m5C (1 time)
|
2005 The language of methylation in genomics of eukaryotes.
|
| 16 |
hemi-methylated, and fully methylated N6-methyladenine
(1 time)
|
Biochemistry
(1 time)
|
m5C (1 time)
|
1990 Analysis of substrate specificity of the PaeR7 endonuclease: effect of base methylation on the kinetics of cleavage.
|
| 17 |
kit-8,N6-methyladenosine
(1 time)
|
Medicine
(1 time)
|
AML (1 time)
METTL3 (1 time)
|
2018 [Methyltransferase-like 3 Promotes the Proliferation of Acute Myeloid Leukemia Cells by Regulating N6-methyladenosine Levels of MYC].
|
| 18 |
M2 activation by targeting tuberous sclerosis 1 via an N6-methyladenosine
(1 time)
|
Biomedical Research
(1 time)
|
IL-4 (1 time)
mRNA (1 time)
STAT6 (1 time)
|
2021 The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ.
|
| 19 |
m6A, and methylated
(1 time)
|
Vascular Diseases
(1 time)
|
FTO (1 time)
|
2018 FTO-Dependent N6-Methyladenosine Regulates Cardiac Function During Remodeling and Repair.
|
| 20 |
m6A-Atlas: a comprehensive knowledgebase for unraveling the N6-methyladenosine
(1 time)
|
Biochemistry
(1 time)
|
---
|
2020 m6A-Atlas: a comprehensive knowledgebase for unraveling the N6-methyladenosine (m6A) epitranscriptome.
|
| 21 |
m6Am rather than N6-methyladenosine
(1 time)
|
Science
(1 time)
|
FTO (1 time)
|
2016 Reversible methylation of m6Am in the 5' cap controls mRNA stability.
|
| 22 |
mammalian messenger RNA, N6methyladenosine
(1 time)
|
Neoplasms
(1 time)
|
EMT (1 time)
|
2018 METTL3 promotes ovarian carcinoma growth and invasion through the regulation of AXL translation and epithelial to mesenchymal transition.
|
| 23 |
markers and prognostic performance of N6-methyladenosine
(1 time)
|
Biomedical Research
(1 time)
|
CM (1 time)
CNV (1 time)
SNP (1 time)
|
2021 Identification and Verification of Molecular Subtypes with Enhanced Immune Infiltration Based on m6A Regulators in Cutaneous Melanoma.
|
| 24 |
mechanism of N6.methyladenosine
(1 time)
|
Epigenesis, Genetic
(1 time)
|
IDD (1 time)
|
2020 Bioinformatics analysis integrating metabolomics of m6A RNA microarray in intervertebral disc degeneration.
|
| 25 |
mechanism of the RNA N6,2'-O-dimethyladenosine
(1 time)
|
Neoplasms
(1 time)
|
METTL3 (1 time)
RIP (1 time)
UBXN1 (1 time)
|
2021 YTHDF2 facilitates UBXN1 mRNA decay by recognizing METTL3-mediated m6A modification to activate NF-κB and promote the malignant progression of glioma.
|
| 26 |
Mechanistically, FEZF1AS1 expression was influenced by N6methyladenosine
(1 time)
|
Neoplasms
(1 time)
|
lncRNAs (1 time)
miR (1 time)
NSCLC (1 time)
|
2020 Long non‑coding RNA FEZF1‑AS1 facilitates non‑small cell lung cancer progression via the ITGA11/miR‑516b‑5p axis.
|
| 27 |
messenger RNA, such as N6-methyladenosine
(1 time)
|
Genetics, Medical
(1 time)
|
---
|
2020 N6-Methyladenosine co-transcriptionally directs the demethylation of histone H3K9me2.
|
| 28 |
messenger RNAs identified, N6-methyladenosine
(1 time)
|
Genetics
(1 time)
|
---
|
2017 Role of N6-methyladenosine modification in cancer.
|
| 29 |
methylated at internal adenosine residues to form N6-methyladenosine
(1 time)
|
Molecular Biology
(1 time)
|
---
|
1987 Unequal distribution of N6-methyladenosine in influenza virus mRNAs.
|
| 30 |
methylated at the N6 position of A to form N6-methyladenine
(1 time)
|
|
8-oxo-dGTP (1 time)
8-oxodG (1 time)
HG (1 time)
|
2018 The m6A methylation perturbs the Hoogsteen pairing-guided incorporation of an oxidized nucleotide.
|
| 31 |
methylation and demethylation of N6-methyladenosine
(1 time)
|
Biological Science Disciplines
(1 time)
|
m6ACE-seq (1 time)
|
2019 Atlas of quantitative single-base-resolution N6-methyl-adenine methylomes.
|
| 32 |
methylation and post-transcriptionally by N-6-methyladenosine
(1 time)
|
Epigenesis, Genetic
(1 time)
|
FA (1 time)
|
2020 Fusaric acid decreases p53 expression by altering promoter methylation and m6A RNA methylation in human hepatocellular carcinoma (HepG2) cells.
|
| 33 |
methylation at position N6 in adenosine
(1 time)
|
Neoplasms
(1 time)
|
lncRNAs (1 time)
mCRPC (1 time)
MTC (1 time)
|
2020 VIRMA-Dependent N6-Methyladenosine Modifications Regulate the Expression of Long Non-Coding RNAs CCAT1 and CCAT2 in Prostate Cancer.
|
| 34 |
methylation at position N6 of adenine is called N6-methyladenosine
(1 time)
|
Genetic Phenomena
(1 time)
|
DFI (1 time)
DSS (1 time)
GO (1 time)
|
2021 Contributions and Prognostic Values of N6-Methyladenosine RNA Methylation Regulators in Hepatocellular Carcinoma.
|
| 35 |
methylation of messenger RNA at the N6 position
(1 time)
|
Embryology
(1 time)
|
---
|
2020 Dm Ime4 depletion affects permeability barrier and Chic function in Drosophila spermatogenesis.
|
| 36 |
methylation such as N6-methyladenosine
(1 time)
|
Molecular Biology
(1 time)
|
---
|
2020 The cardiac methylome: A hidden layer of RNA modifications to regulate gene expression.
|
| 37 |
methylations of adenosine to form either N 6-methyladenosine
(1 time)
|
Molecular Biology
(1 time)
|
m6Am (1 time)
mRNA (1 time)
|
2019 Discovering and Mapping the Modified Nucleotides That Comprise the Epitranscriptome of mRNA.
|
| 38 |
methyltransferase that catalyzes the abundant N6-methyladenosine
(1 time)
|
Cells
(1 time)
|
ADPKD (1 time)
SAM (1 time)
|
2021 A methionine-Mettl3-N6-methyladenosine axis promotes polycystic kidney disease.
|
| 39 |
METTL14 and N6-adenosine methylation
(1 time)
|
Chemistry
(1 time)
|
HDAC (1 time)
mESCs (1 time)
TSA (1 time)
|
2020 The Distinct Function and Localization of METTL3/METTL14 and METTL16 Enzymes in Cardiomyocytes.
|
| 40 |
METTL14, as one of N6-methyladenosine
(1 time)
|
Cell Transformation, Neoplastic
(1 time)
|
ccRCC (1 time)
GSEA (1 time)
OS (1 time)
|
2021 Decreased expression of METTL14 predicts poor prognosis and construction of a prognostic signature for clear cell renal cell carcinoma.
|
| 41 |
METTL3, an enzyme catalyzes the formation of N6-methyladenosine
(1 time)
|
Biophysics
(1 time)
|
ECM (1 time)
OA (1 time)
|
2019 METTL3 promotes experimental osteoarthritis development by regulating inflammatory response and apoptosis in chondrocyte.
|
| 42 |
METTL3, an RNA N6-methyladenosine
(1 time)
|
Cell Biology
(1 time)
|
---
|
2018 METTL3-mediated N6-methyladenosine mRNA modification enhances long-term memory consolidation.
|
| 43 |
modification and regulation of N6-methyladenosine
(1 time)
|
Translational Medical Research
(1 time)
|
RCC (1 time)
RIP (1 time)
|
2020 ALKBH5 promotes the proliferation of renal cell carcinoma by regulating AURKB expression in an m6A-dependent manner.
|
| 44 |
modifications after transcription, such as N6-methyladenosine
(1 time)
|
Gastroenterology
(1 time)
|
---
|
2020 Epitranscriptomics in liver disease: Basic concepts and therapeutic potential.
|
| 45 |
modifications and, in particular, for N6-methyladenosine
(1 time)
|
Medical Informatics
(1 time)
|
MeRIP-seq (1 time)
MoAIMS (1 time)
|
2020 MoAIMS: efficient software for detection of enriched regions of MeRIP-Seq.
|
| 46 |
modifications are known, such as 6-methyladenosine
(1 time)
|
|
AML (1 time)
HSPCs (1 time)
m5C (1 time)
|
2021 Immunotherapeutic Potential of m6A-Modifiers and MicroRNAs in Controlling Acute Myeloid Leukaemia.
|
| 47 |
modifications of DNA and RNA, with particular focus on N6-methyladenosine
(1 time)
|
Neoplasms
(1 time)
|
HDACs (1 time)
MAR (1 time)
|
2020 Epigenetic deregulation in cancer: Enzyme players and non-coding RNAs.
|
| 48 |
modifications, among which N6-methyladenosine
(1 time)
|
Science
(1 time)
|
---
|
2019 Development and validation of monoclonal antibodies against N6-methyladenosine for the detection of RNA modifications.
|
| 49 |
modified nucleotides are N6-methyladenosine
(1 time)
|
Molecular Biology
(1 time)
|
m6Am (1 time)
TSSs (1 time)
|
2019 Identification of the m6Am Methyltransferase PCIF1 Reveals the Location and Functions of m6Am in the Transcriptome.
|
| 50 |
modulated by the writer, eraser, and reader proteins of N6-methyladenosine
(1 time)
|
Biological Science Disciplines
(1 time)
|
---
|
2019 HSP90 inhibitors stimulate DNAJB4 protein expression through a mechanism involving N6-methyladenosine.
|
| 51 |
monomethylating the N6-atom of adenine
(1 time)
|
RNA
(1 time)
|
MTases (1 time)
SAM (1 time)
|
2019 Bisubstrate analogues as structural tools to investigate m6A methyltransferase active sites.
|
| 52 |
most abundant among them is N6-methyladenosine
(1 time)
|
Biological Science Disciplines
(1 time)
|
YTHDF3 (1 time)
|
2018 Dynamic m6A methylation facilitates mRNA triaging to stress granules.
|
| 53 |
most abundant mRNA modification, N6-methyladenosine
(1 time)
|
Science
(1 time)
|
Tg (1 time)
|
2019 Epitranscriptomics: Correlation of N6-methyladenosine RNA methylation and pathway dysregulation in the hippocampus of HIV transgenic rats.
|
| 54 |
most common of which is the N6methyladenosine
(1 time)
|
Genes, Regulator
(1 time)
|
---
|
2018 The m6A‑methylase complex and mRNA export.
|
| 55 |
mRNA and suppressed its stability through interaction with the N6-methyladenosine
(1 time)
|
Biophysics
(1 time)
|
GC (1 time)
lncRNA (1 time)
|
2019 LncRNA LINC00470 promotes the degradation of PTEN mRNA to facilitate malignant behavior in gastric cancer cells.
|
| 56 |
mRNAs, N6-adenosine methylation
(1 time)
|
Genes, Regulator
(1 time)
|
---
|
2018 The role of RNA adenosine demethylases in the control of gene expression.
|
| 57 |
N4-methylcytosine and N6-methyladenine
(1 time)
|
Biochemistry
(1 time)
|
---
|
2006 Undetectable levels of N6-methyl adenine in mouse DNA: Cloning and analysis of PRED28, a gene coding for a putative mammalian DNA adenine methyltransferase.
|
| 58 |
N6-methyl-A
(1 time)
|
Biochemistry
(1 time)
|
m7G (2 times)
m1G (1 time)
m5C (1 time)
|
1984 Antibody-nucleic acid complexes. Antigenic domains within nucleosides as defined by solid-phase immunoassay.
|
| 59 |
N6-methylation
(1 time)
|
Embryology
(1 time)
|
---
|
2021 RNA demethylation by FTO stabilizes the FOXJ1 mRNA for proper motile ciliogenesis.
|
| 60 |
N6-methylation found on adenosine
(1 time)
|
Biochemistry
(1 time)
|
MTases (1 time)
|
2021 A comprehensive review of m6A/m6Am RNA methyltransferase structures.
|
| 61 |
N6-methylation of internal adenosines
(1 time)
|
Science
(1 time)
|
Ck1delta (1 time)
|
2018 Two Ck1delta transcripts regulated by m6A methylation code for two antagonistic kinases in the control of the circadian clock.
|
| 62 |
N6-methyldeoxyadenine
(1 time)
|
Molecular Biology
(1 time)
|
m5C (1 time)
MTases (1 time)
|
1997 Chlorella virus SC-1A encodes at least five functional and one nonfunctional DNA methyltransferases.
|
| 63 |
N6-monomethyl adenine
(1 time)
|
Bacteriology
(1 time)
|
rRNA (1 time)
|
1975 Systematic difference in the methylation of ribosomal ribonucleic acid from gram-positive and gram-negative bacteria.
|
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