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Abbreviation: m6A
Appearance Frequency: 1524 time(s)
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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
N6-methyladenosine
(1402 times)
Neoplasms
(222 times)
METTL3 (96 times)
FTO (77 times)
mRNA (62 times)
1976 5'-Terminal and internal methylated nucleotide sequences in HeLa cell mRNA.
N6-methylation of adenosine
(18 times)
Neoplasms
(4 times)
GSEA (2 times)
ROC (2 times)
YTH (2 times)
2015 N6-adenosine methylation in MiRNAs.
Methylation at the N6 position of adenosine
(14 times)
Microbiology
(2 times)
HA (2 times)
CLIP (1 time)
ds (1 time)
2017 Viral Epitranscriptomics.
modification is N6-methyladenosine
(13 times)
Cell Biology
(2 times)
DNA (1 time)
FDmMGenes (1 time)
LASSO (1 time)
2017 Detecting N6-methyladenosine sites from RNA transcriptomes using ensemble Support Vector Machines.
mRNAs, N6-methyladenosine
(6 times)
Biochemistry
(2 times)
BioID (1 time)
KRT7 (1 time)
MAGE (1 time)
2018 The m6A Writer: Rise of a Machine for Growing Tasks.
methylation of adenosine at the N6-position
(4 times)
Chemistry
(1 time)
m1A (1 time)
mRNA (1 time)
RNA MTases (1 time)
2019 m6A-mRNA methylation regulates cardiac gene expression and cellular growth.
methyl groups at the N6 position
(3 times)
Botany
(1 time)
8-NO2-G (1 time)
CTD (1 time)
m5C (1 time)
2018 Addition of m6A to SV40 late mRNAs enhances viral structural gene expression and replication.
N6-methylated adenine
(3 times)
Biochemistry
(2 times)
N6-mAMP (1 time)
2018 m6A RNA Degradation Products Are Catabolized by an Evolutionarily Conserved N6-Methyl-AMP Deaminase in Plant and Mammalian Cells.
m2G and N6-methyladenosine
(2 times)
Bacteriology
(1 time)
m1A (1 time)
m2G (1 time)
m6G (1 time)
1979 23S ribosomal ribonucleic acid of macrolide-producing streptomycetes contains methylated adenine.
10  methyl-6-adenosine
(2 times)
Biochemistry
(1 time)
5mC (1 time)
LINE (1 time)
m5C (1 time)
2017 Illustrating the Epitranscriptome at Nucleotide Resolution Using Methylation-iCLIP (miCLIP).
11  Methylation of the adenosine base at the nitrogen-6 position
(2 times)
Molecular Biology
(2 times)
ABEs (1 time)
SNP (1 time)
2017 Most m6A RNA Modifications in Protein-Coding Regions Are Evolutionarily Unconserved and Likely Nonfunctional.
12  modification in eukaryotic cells, N 6-methyladenosine
(2 times)
Cell Biology
(1 time)
KSHV (1 time)
SV40 (1 time)
2018 The RNA Epitranscriptome of DNA Viruses.
13  modifiers are N6-methyladenosine
(2 times)
Medicine
(1 time)
IGF2BP2 (1 time)
KD (1 time)
KO (1 time)
2019 IGF2BP2 regulates DANCR by serving as an N6-methyladenosine reader.
14  mRNA and noncoding RNAs is N6-methyladenosine
(2 times)
Toxicology
(1 time)
GC (1 time)
GSEA (1 time)
MeRIP-seq (1 time)
2019 Reduced m6A modification predicts malignant phenotypes and augmented Wnt/PI3K-Akt signaling in gastric cancer.
15  6-methylaminopurine
(1 time)
Biochemistry
(1 time)
m5C (1 time)
2005 The language of methylation in genomics of eukaryotes.
16  hemi-methylated, and fully methylated N6-methyladenine
(1 time)
Biochemistry
(1 time)
m5C (1 time)
1990 Analysis of substrate specificity of the PaeR7 endonuclease: effect of base methylation on the kinetics of cleavage.
17  kit-8,N6-methyladenosine
(1 time)
Medicine
(1 time)
AML (1 time)
METTL3 (1 time)
2018 [Methyltransferase-like 3 Promotes the Proliferation of Acute Myeloid Leukemia Cells by Regulating N6-methyladenosine Levels of MYC].
18  M2 activation by targeting tuberous sclerosis 1 via an N6-methyladenosine
(1 time)
Biomedical Research
(1 time)
IL-4 (1 time)
mRNA (1 time)
STAT6 (1 time)
2021 The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ.
19  m6A, and methylated
(1 time)
Vascular Diseases
(1 time)
FTO (1 time)
2018 FTO-Dependent N6-Methyladenosine Regulates Cardiac Function During Remodeling and Repair.
20  m6A-Atlas: a comprehensive knowledgebase for unraveling the N6-methyladenosine
(1 time)
Biochemistry
(1 time)
--- 2020 m6A-Atlas: a comprehensive knowledgebase for unraveling the N6-methyladenosine (m6A) epitranscriptome.
21  m6Am rather than N6-methyladenosine
(1 time)
Science
(1 time)
FTO (1 time)
2016 Reversible methylation of m6Am in the 5' cap controls mRNA stability.
22  mammalian messenger RNA, N6methyladenosine
(1 time)
Neoplasms
(1 time)
EMT (1 time)
2018 METTL3 promotes ovarian carcinoma growth and invasion through the regulation of AXL translation and epithelial to mesenchymal transition.
23  markers and prognostic performance of N6-methyladenosine
(1 time)
Biomedical Research
(1 time)
CM (1 time)
CNV (1 time)
SNP (1 time)
2021 Identification and Verification of Molecular Subtypes with Enhanced Immune Infiltration Based on m6A Regulators in Cutaneous Melanoma.
24  mechanism of N6.methyladenosine
(1 time)
Epigenesis, Genetic
(1 time)
IDD (1 time)
2020 Bioinformatics analysis integrating metabolomics of m6A RNA microarray in intervertebral disc degeneration.
25  mechanism of the RNA N6,2'-O-dimethyladenosine
(1 time)
Neoplasms
(1 time)
METTL3 (1 time)
RIP (1 time)
UBXN1 (1 time)
2021 YTHDF2 facilitates UBXN1 mRNA decay by recognizing METTL3-mediated m6A modification to activate NF-κB and promote the malignant progression of glioma.
26  Mechanistically, FEZF1AS1 expression was influenced by N6methyladenosine
(1 time)
Neoplasms
(1 time)
lncRNAs (1 time)
miR (1 time)
NSCLC (1 time)
2020 Long non‑coding RNA FEZF1‑AS1 facilitates non‑small cell lung cancer progression via the ITGA11/miR‑516b‑5p axis.
27  messenger RNA, such as N6-methyladenosine
(1 time)
Genetics, Medical
(1 time)
--- 2020 N6-Methyladenosine co-transcriptionally directs the demethylation of histone H3K9me2.
28  messenger RNAs identified, N6-methyladenosine
(1 time)
Genetics
(1 time)
--- 2017 Role of N6-methyladenosine modification in cancer.
29  methylated at internal adenosine residues to form N6-methyladenosine
(1 time)
Molecular Biology
(1 time)
--- 1987 Unequal distribution of N6-methyladenosine in influenza virus mRNAs.
30  methylated at the N6 position of A to form N6-methyladenine
(1 time)
8-oxo-dGTP (1 time)
8-oxodG (1 time)
HG (1 time)
2018 The m6A methylation perturbs the Hoogsteen pairing-guided incorporation of an oxidized nucleotide.
31  methylation and demethylation of N6-methyladenosine
(1 time)
Biological Science Disciplines
(1 time)
m6ACE-seq (1 time)
2019 Atlas of quantitative single-base-resolution N6-methyl-adenine methylomes.
32  methylation and post-transcriptionally by N-6-methyladenosine
(1 time)
Epigenesis, Genetic
(1 time)
FA (1 time)
2020 Fusaric acid decreases p53 expression by altering promoter methylation and m6A RNA methylation in human hepatocellular carcinoma (HepG2) cells.
33  methylation at position N6 in adenosine
(1 time)
Neoplasms
(1 time)
lncRNAs (1 time)
mCRPC (1 time)
MTC (1 time)
2020 VIRMA-Dependent N6-Methyladenosine Modifications Regulate the Expression of Long Non-Coding RNAs CCAT1 and CCAT2 in Prostate Cancer.
34  methylation at position N6 of adenine is called N6-methyladenosine
(1 time)
Genetic Phenomena
(1 time)
DFI (1 time)
DSS (1 time)
GO (1 time)
2021 Contributions and Prognostic Values of N6-Methyladenosine RNA Methylation Regulators in Hepatocellular Carcinoma.
35  methylation of messenger RNA at the N6 position
(1 time)
Embryology
(1 time)
--- 2020 Dm Ime4 depletion affects permeability barrier and Chic function in Drosophila spermatogenesis.
36  methylation such as N6-methyladenosine
(1 time)
Molecular Biology
(1 time)
--- 2020 The cardiac methylome: A hidden layer of RNA modifications to regulate gene expression.
37  methylations of adenosine to form either N 6-methyladenosine
(1 time)
Molecular Biology
(1 time)
m6Am (1 time)
mRNA (1 time)
2019 Discovering and Mapping the Modified Nucleotides That Comprise the Epitranscriptome of mRNA.
38  methyltransferase that catalyzes the abundant N6-methyladenosine
(1 time)
Cells
(1 time)
ADPKD (1 time)
SAM (1 time)
2021 A methionine-Mettl3-N6-methyladenosine axis promotes polycystic kidney disease.
39  METTL14 and N6-adenosine methylation
(1 time)
Chemistry
(1 time)
HDAC (1 time)
mESCs (1 time)
TSA (1 time)
2020 The Distinct Function and Localization of METTL3/METTL14 and METTL16 Enzymes in Cardiomyocytes.
40  METTL14, as one of N6-methyladenosine
(1 time)
Cell Transformation, Neoplastic
(1 time)
ccRCC (1 time)
GSEA (1 time)
OS (1 time)
2021 Decreased expression of METTL14 predicts poor prognosis and construction of a prognostic signature for clear cell renal cell carcinoma.
41  METTL3, an enzyme catalyzes the formation of N6-methyladenosine
(1 time)
Biophysics
(1 time)
ECM (1 time)
OA (1 time)
2019 METTL3 promotes experimental osteoarthritis development by regulating inflammatory response and apoptosis in chondrocyte.
42  METTL3, an RNA N6-methyladenosine
(1 time)
Cell Biology
(1 time)
--- 2018 METTL3-mediated N6-methyladenosine mRNA modification enhances long-term memory consolidation.
43  modification and regulation of N6-methyladenosine
(1 time)
Translational Medical Research
(1 time)
RCC (1 time)
RIP (1 time)
2020 ALKBH5 promotes the proliferation of renal cell carcinoma by regulating AURKB expression in an m6A-dependent manner.
44  modifications after transcription, such as N6-methyladenosine
(1 time)
Gastroenterology
(1 time)
--- 2020 Epitranscriptomics in liver disease: Basic concepts and therapeutic potential.
45  modifications and, in particular, for N6-methyladenosine
(1 time)
Medical Informatics
(1 time)
MeRIP-seq (1 time)
MoAIMS (1 time)
2020 MoAIMS: efficient software for detection of enriched regions of MeRIP-Seq.
46  modifications are known, such as 6-methyladenosine
(1 time)
AML (1 time)
HSPCs (1 time)
m5C (1 time)
2021 Immunotherapeutic Potential of m6A-Modifiers and MicroRNAs in Controlling Acute Myeloid Leukaemia.
47  modifications of DNA and RNA, with particular focus on N6-methyladenosine
(1 time)
Neoplasms
(1 time)
HDACs (1 time)
MAR (1 time)
2020 Epigenetic deregulation in cancer: Enzyme players and non-coding RNAs.
48  modifications, among which N6-methyladenosine
(1 time)
Science
(1 time)
--- 2019 Development and validation of monoclonal antibodies against N6-methyladenosine for the detection of RNA modifications.
49  modified nucleotides are N6-methyladenosine
(1 time)
Molecular Biology
(1 time)
m6Am (1 time)
TSSs (1 time)
2019 Identification of the m6Am Methyltransferase PCIF1 Reveals the Location and Functions of m6Am in the Transcriptome.
50  modulated by the writer, eraser, and reader proteins of N6-methyladenosine
(1 time)
Biological Science Disciplines
(1 time)
--- 2019 HSP90 inhibitors stimulate DNAJB4 protein expression through a mechanism involving N6-methyladenosine.
51  monomethylating the N6-atom of adenine
(1 time)
RNA
(1 time)
MTases (1 time)
SAM (1 time)
2019 Bisubstrate analogues as structural tools to investigate m6A methyltransferase active sites.
52  most abundant among them is N6-methyladenosine
(1 time)
Biological Science Disciplines
(1 time)
YTHDF3 (1 time)
2018 Dynamic m6A methylation facilitates mRNA triaging to stress granules.
53  most abundant mRNA modification, N6-methyladenosine
(1 time)
Science
(1 time)
Tg (1 time)
2019 Epitranscriptomics: Correlation of N6-methyladenosine RNA methylation and pathway dysregulation in the hippocampus of HIV transgenic rats.
54  most common of which is the N6methyladenosine
(1 time)
Genes, Regulator
(1 time)
--- 2018 The m6A‑methylase complex and mRNA export.
55  mRNA and suppressed its stability through interaction with the N6-methyladenosine
(1 time)
Biophysics
(1 time)
GC (1 time)
lncRNA (1 time)
2019 LncRNA LINC00470 promotes the degradation of PTEN mRNA to facilitate malignant behavior in gastric cancer cells.
56  mRNAs, N6-adenosine methylation
(1 time)
Genes, Regulator
(1 time)
--- 2018 The role of RNA adenosine demethylases in the control of gene expression.
57  N4-methylcytosine and N6-methyladenine
(1 time)
Biochemistry
(1 time)
--- 2006 Undetectable levels of N6-methyl adenine in mouse DNA: Cloning and analysis of PRED28, a gene coding for a putative mammalian DNA adenine methyltransferase.
58  N6-methyl-A
(1 time)
Biochemistry
(1 time)
m7G (2 times)
m1G (1 time)
m5C (1 time)
1984 Antibody-nucleic acid complexes. Antigenic domains within nucleosides as defined by solid-phase immunoassay.
59  N6-methylation
(1 time)
Embryology
(1 time)
--- 2021 RNA demethylation by FTO stabilizes the FOXJ1 mRNA for proper motile ciliogenesis.
60  N6-methylation found on adenosine
(1 time)
Biochemistry
(1 time)
MTases (1 time)
2021 A comprehensive review of m6A/m6Am RNA methyltransferase structures.
61  N6-methylation of internal adenosines
(1 time)
Science
(1 time)
Ck1delta (1 time)
2018 Two Ck1delta transcripts regulated by m6A methylation code for two antagonistic kinases in the control of the circadian clock.
62  N6-methyldeoxyadenine
(1 time)
Molecular Biology
(1 time)
m5C (1 time)
MTases (1 time)
1997 Chlorella virus SC-1A encodes at least five functional and one nonfunctional DNA methyltransferases.
63  N6-monomethyl adenine
(1 time)
Bacteriology
(1 time)
rRNA (1 time)
1975 Systematic difference in the methylation of ribosomal ribonucleic acid from gram-positive and gram-negative bacteria.