| 1 |
mammalian target of rapamycin complex 1
(1742 times)
|
Cell Biology
(262 times)
|
AMPK (121 times)
TSC (99 times)
PI3K (63 times)
|
2006 S6K1 regulates GSK3 under conditions of mTOR-dependent feedback inhibition of Akt.
|
| 2 |
mTOR complex 1
(601 times)
|
Neoplasms
(99 times)
|
mTOR (348 times)
mTORC2 (105 times)
AMPK (40 times)
|
2006 Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML.
|
| 3 |
mammalian TORC1
(12 times)
|
Cell Biology
(4 times)
|
TORC1 (8 times)
TOR (3 times)
4EBP1 (1 time)
|
2008 Hypoxia regulates TSC1/2-mTOR signaling and tumor suppression through REDD1-mediated 14-3-3 shuttling.
|
| 4 |
mammalian TOR complex 1
(4 times)
|
Cell Biology
(3 times)
|
TOR (2 times)
PPAR (1 time)
S6K (1 time)
|
2008 Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration.
|
| 5 |
mammalian isoform of the target of rapamycin complex 1
(2 times)
|
Neuroanatomy
(1 time)
|
TSC (2 times)
GAP (1 time)
KD (1 time)
|
2020 The Neurodevelopmental Pathogenesis of Tuberous Sclerosis Complex (TSC).
|
| 6 |
manipulations of mTOR complex 1
(2 times)
|
Chemistry
(1 time)
|
mTOR (1 time)
|
2013 Hypothalamic mTORC1 signaling controls sympathetic nerve activity and arterial pressure and mediates leptin effects.
|
| 7 |
mTOR protein complex-1
(2 times)
|
Biochemistry
(1 time)
|
eIF4E (1 time)
EtOH (1 time)
HFS (1 time)
|
2009 Novel translational control in Arc-dependent long term potentiation consolidation in vivo.
|
| 8 |
mTOR-containing complex 1
(2 times)
|
Medicine
(2 times)
|
CTCL (2 times)
eIF4E (1 time)
p70S6K1 (1 time)
|
2011 Simultaneous inhibition of mTOR-containing complex 1 (mTORC1) and MNK induces apoptosis of cutaneous T-cell lymphoma (CTCL) cells.
|
| 9 |
3-kinase-AKT-mTOR complex 1
(1 time)
|
Cell Biology
(1 time)
|
CNS (1 time)
PTEN (1 time)
|
2019 AKT-dependent and -independent pathways mediate PTEN deletion-induced CNS axon regeneration.
|
| 10 |
Akt-mTOR complex 1
(1 time)
|
Science
(1 time)
|
---
|
2020 LIN28B/let-7 control the ability of neonatal murine auditory supporting cells to generate hair cells through mTOR signaling.
|
| 11 |
macrophage activation by inhibiting signaling pathways involved in M1
(1 time)
|
Biochemistry
(1 time)
|
---
|
2020 Curcumin steers THP-1 cells under LPS and mTORC1 challenges toward phenotypically resting, low cytokine-producing macrophages.
|
| 12 |
mammalian counterpart of TORC1
(1 time)
|
Cell Biology
(1 time)
|
mTORC2 (1 time)
TOR (1 time)
|
2004 Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive.
|
| 13 |
mammalian rapamycin target protein complex 1
(1 time)
|
Drug Therapy
(1 time)
|
BDNF (1 time)
GABAA (1 time)
Glu (1 time)
|
2020 A hypothesis of monoamine (5-HT) - Glutamate/GABA long neural circuit: Aiming for fast-onset antidepressant discovery.
|
| 14 |
mammalian target of TOR complex 1
(1 time)
|
Pathology
(1 time)
|
AS-IV (1 time)
MI (1 time)
|
2013 Genetic and pharmacological inhibition of Rheb1-mTORC1 signaling exerts cardioprotection against adverse cardiac remodeling in mice.
|
| 15 |
mechanistic rapamycin complex 1
(1 time)
|
Genetics
(1 time)
|
---
|
2016 Mutations of RagA GTPase in mTORC1 Pathway Are Associated with Autosomal Dominant Cataracts.
|
| 16 |
mechanistic TORC1
(1 time)
|
Biochemistry
(1 time)
|
TORC1 (1 time)
|
2013 A positive role of mammalian Tip41-like protein, TIPRL, in the amino-acid dependent mTORC1-signaling pathway through interaction with PP2A.
|
| 17 |
Mechanistically, high activity ofmammalian target of rapamycin complex 1
(1 time)
|
Science
(1 time)
|
PPAR-alpha (1 time)
|
2019 Notum produced by Paneth cells attenuates regeneration of aged intestinal epithelium.
|
| 18 |
mediator of mTOR complex 1
(1 time)
|
Science
(1 time)
|
mTOR (1 time)
SAD-A (1 time)
|
2013 SAD-A kinase controls islet beta-cell size and function as a mediator of mTORC1 signaling.
|
| 19 |
mitochondrial target of rapamycin complex 1
(1 time)
|
Science
(1 time)
|
FOXO3a (1 time)
iCMs (1 time)
IGF1 (1 time)
|
2015 Akt1/protein kinase B enhances transcriptional reprogramming of fibroblasts to functional cardiomyocytes.
|
| 20 |
mTOR 1 complex
(1 time)
|
Chemistry
(1 time)
|
GAs (1 time)
mTOR (1 time)
mTORC2 (1 time)
|
2018 Early Developmental Exposure to General Anesthetic Agents in Primary Neuron Culture Disrupts Synapse Formation via Actions on the mTOR Pathway.
|
| 21 |
mTOR have been identified: complex 1
(1 time)
|
Biochemistry
(1 time)
|
NDRG1 (1 time)
S6K (1 time)
|
2011 Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney.
|
| 22 |
mTOR or mTOR complex 1
(1 time)
|
Adipocytes
(1 time)
|
BAT (1 time)
DKO (1 time)
HFD (1 time)
|
2018 Elucidating the role of Lkb1 and mTOR in adipose tissue.
|
| 23 |
mTOR signaling complex 1
(1 time)
|
Neoplasms
(1 time)
|
mTOR (1 time)
mTORC2 (1 time)
|
2009 TORC-specific phosphorylation of mammalian target of rapamycin (mTOR): phospho-Ser2481 is a marker for intact mTOR signaling complex 2.
|
| 24 |
multi-protein complexes known as complex 1
(1 time)
|
Neoplasms
(1 time)
|
mTOR (1 time)
|
2013 Prognostic and therapeutic implications of mTORC1 and Rictor expression in human breast cancer.
|
| 25 |
phospho-mTOR complex 1
(1 time)
|
Neurology
(1 time)
|
mTOR (1 time)
|
2017 Effects of escitalopram and paroxetine on mTORC1 signaling in the rat hippocampus under chronic restraint stress.
|
| 26 |
PTEN-PI3K-mTOR complex 1
(1 time)
|
Neoplasms
(1 time)
|
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|
2018 Polyamine metabolism and cancer: treatments, challenges andopportunities.
|
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