1 |
mammalian target of rapamycin complex 1
(1926 times)
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Cell Biology (288 times)
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AMPK (132 times) TSC (103 times) PI3K (66 times)
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2006 S6K1 regulates GSK3 under conditions of mTOR-dependent feedback inhibition of Akt.
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2 |
mTOR complex 1
(641 times)
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Neoplasms (102 times)
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mTOR (373 times) mTORC2 (111 times) AMPK (42 times)
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2006 Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML.
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3 |
mammalian TORC1
(13 times)
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Cell Biology (4 times)
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TORC1 (8 times) TOR (3 times) 4EBP1 (1 time)
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2008 Hypoxia regulates TSC1/2-mTOR signaling and tumor suppression through REDD1-mediated 14-3-3 shuttling.
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4 |
mammalian TOR complex 1
(4 times)
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Cell Biology (3 times)
|
TOR (2 times) PPAR (1 time) S6K (1 time)
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2008 Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration.
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5 |
Modulation of mTOR complex 1
(3 times)
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Chemistry (1 time)
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MT (1 time) mTOR (1 time) NPSI (1 time)
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2013 Hypothalamic mTORC1 signaling controls sympathetic nerve activity and arterial pressure and mediates leptin effects.
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6 |
mammalian isoform of the target of rapamycin complex 1
(2 times)
|
Neuroanatomy (1 time)
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TSC (2 times) GAP (1 time) KD (1 time)
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2020 The Neurodevelopmental Pathogenesis of Tuberous Sclerosis Complex (TSC).
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7 |
mediator of mTOR complex 1
(2 times)
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Science (1 time)
|
mTOR (1 time) SAD-A (1 time)
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2013 SAD-A kinase controls islet beta-cell size and function as a mediator of mTORC1 signaling.
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8 |
mTOR protein complex-1
(2 times)
|
Biochemistry (1 time)
|
eIF4E (1 time) EtOH (1 time) HFS (1 time)
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2009 Novel translational control in Arc-dependent long term potentiation consolidation in vivo.
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9 |
mTOR-containing complex 1
(2 times)
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Medicine (2 times)
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CTCL (2 times) eIF4E (1 time) p70S6K1 (1 time)
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2011 Simultaneous inhibition of mTOR-containing complex 1 (mTORC1) and MNK induces apoptosis of cutaneous T-cell lymphoma (CTCL) cells.
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10 |
3-kinase-AKT-mTOR complex 1
(1 time)
|
Cell Biology (1 time)
|
CNS (1 time) PTEN (1 time)
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2019 AKT-dependent and -independent pathways mediate PTEN deletion-induced CNS axon regeneration.
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11 |
Akt-mTOR complex 1
(1 time)
|
Science (1 time)
|
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2020 LIN28B/let-7 control the ability of neonatal murine auditory supporting cells to generate hair cells through mTOR signaling.
|
12 |
macrophage activation by inhibiting signaling pathways involved in M1
(1 time)
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Biochemistry (1 time)
|
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2020 Curcumin steers THP-1 cells under LPS and mTORC1 challenges toward phenotypically resting, low cytokine-producing macrophages.
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13 |
mammalian counterpart of TORC1
(1 time)
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Cell Biology (1 time)
|
mTORC2 (1 time) TOR (1 time)
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2004 Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive.
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14 |
mammalian rapamycin target protein complex 1
(1 time)
|
Drug Therapy (1 time)
|
BDNF (1 time) GABAA (1 time) Glu (1 time)
|
2020 A hypothesis of monoamine (5-HT) - Glutamate/GABA long neural circuit: Aiming for fast-onset antidepressant discovery.
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15 |
mammalian target of TOR complex 1
(1 time)
|
Pathology (1 time)
|
AS-IV (1 time) MI (1 time)
|
2013 Genetic and pharmacological inhibition of Rheb1-mTORC1 signaling exerts cardioprotection against adverse cardiac remodeling in mice.
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16 |
mechanistic rapamycin complex 1
(1 time)
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Genetics (1 time)
|
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2016 Mutations of RagA GTPase in mTORC1 Pathway Are Associated with Autosomal Dominant Cataracts.
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17 |
mechanistic target of RPM complex 1
(1 time)
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Neurosciences (1 time)
|
ME (1 time) OM (1 time) PGPS (1 time)
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2022 Autophagy Contributes to the Rapamycin-Induced Improvement of Otitis Media.
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18 |
mechanistic TORC1
(1 time)
|
Biochemistry (1 time)
|
TORC1 (1 time)
|
2013 A positive role of mammalian Tip41-like protein, TIPRL, in the amino-acid dependent mTORC1-signaling pathway through interaction with PP2A.
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19 |
Mechanistically, high activity ofmammalian target of rapamycin complex 1
(1 time)
|
Science (1 time)
|
PPAR-alpha (1 time)
|
2019 Notum produced by Paneth cells attenuates regeneration of aged intestinal epithelium.
|
20 |
mitochondrial target of rapamycin complex 1
(1 time)
|
Science (1 time)
|
FOXO3a (1 time) iCMs (1 time) IGF1 (1 time)
|
2015 Akt1/protein kinase B enhances transcriptional reprogramming of fibroblasts to functional cardiomyocytes.
|
21 |
mTOR 1 complex
(1 time)
|
Chemistry (1 time)
|
GAs (1 time) mTOR (1 time) mTORC2 (1 time)
|
2018 Early Developmental Exposure to General Anesthetic Agents in Primary Neuron Culture Disrupts Synapse Formation via Actions on the mTOR Pathway.
|
22 |
mTOR have been identified: complex 1
(1 time)
|
Biochemistry (1 time)
|
NDRG1 (1 time) S6K (1 time)
|
2011 Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney.
|
23 |
mTOR or mTOR complex 1
(1 time)
|
Adipocytes (1 time)
|
BAT (1 time) DKO (1 time) HFD (1 time)
|
2018 Elucidating the role of Lkb1 and mTOR in adipose tissue.
|
24 |
mTOR signaling complex 1
(1 time)
|
Neoplasms (1 time)
|
mTOR (1 time) mTORC2 (1 time)
|
2009 TORC-specific phosphorylation of mammalian target of rapamycin (mTOR): phospho-Ser2481 is a marker for intact mTOR signaling complex 2.
|
25 |
multi-protein complexes known as complex 1
(1 time)
|
Neoplasms (1 time)
|
mTOR (1 time)
|
2013 Prognostic and therapeutic implications of mTORC1 and Rictor expression in human breast cancer.
|
26 |
pathogenesis-mammalian target of rapamycin complex 1
(1 time)
|
Dermatology (1 time)
|
IGF-1 (1 time)
|
2022 What's Diet Got to Do With It? Basic and Clinical Science Behind Diet and Acne.
|
27 |
phospho-mTOR complex 1
(1 time)
|
Neurology (1 time)
|
mTOR (1 time)
|
2017 Effects of escitalopram and paroxetine on mTORC1 signaling in the rat hippocampus under chronic restraint stress.
|
28 |
PTEN-PI3K-mTOR complex 1
(1 time)
|
Neoplasms (1 time)
|
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2018 Polyamine metabolism and cancer: treatments, challenges andopportunities.
|