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Abbreviation: reg
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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
regulatory T
(19 times)
Allergy and Immunology
(6 times)
FOXP3 (2 times)
IBD (2 times)
IL-2 (2 times)
2005 In contrast to effector T cells, CD4+CD25+FoxP3+ regulatory T cells are highly susceptible to CD95 ligand- but not to TCR-mediated cell death.
regenerating protein
(8 times)
Pathology
(1 time)
PAP (2 times)
PSP (2 times)
GF (1 time)
1993 Human regeneration protein/lithostathine genes map to chromosome 2p12.
results suggest that T
(6 times)
Science
(3 times)
aGVHD (1 time)
FoxP3 (1 time)
IT (1 time)
2006 Intratumoral CD4+CD25+ regulatory T-cell-mediated suppression of infiltrating CD4+ T cells in B-cell non-Hodgkin lymphoma.
recent thymic emigrant-T
(4 times)
Neurology
(1 time)
CHF (1 time)
IL (1 time)
MS (1 time)
2008 Interferon beta-induced restoration of regulatory T-cell function in multiple sclerosis is prompted by an increase in newly generated naive regulatory T cells.
resting T
(4 times)
Medicine
(1 time)
T1D (1 time)
2009 Apoptosis of CD4+ CD25(high) T cells in type 1 diabetes may be partially mediated by IL-2 deprivation.
regulates T
(3 times)
Science
(2 times)
TCR (2 times)
5azaD (1 time)
EAE (1 time)
2009 Use of epigenetic modification to induce FOXP3 expression in naive T cells.
reduction of circulating T
(2 times)
Pharmacology
(1 time)
IL (1 time)
2009 Ovarian cancer cytoreduction induces changes in T cell population subsets reducing immunosuppression.
regulatory capacity of T
(2 times)
Transplantation
(1 time)
CWD (1 time)
TCR (1 time)
2011 The potency of allospecific Tregs cells appears to correlate with T cell receptor functional avidity.
regulatory function of T
(2 times)
Allergy and Immunology
(2 times)
FOXP3 (2 times)
GD (1 time)
HD (1 time)
2008 TGFbeta1 deficiency does not affect the generation and maintenance of CD4+CD25+FOXP3+ putative Treg cells, but causes their numerical inadequacy and loss of regulatory function.
10  age-related link among Aire, disease susceptibility, and peripheral T
(1 time)
Science
(1 time)
EAMG (1 time)
WT (1 time)
2013 Experimental myasthenia gravis in Aire-deficient mice: a link between Aire and regulatory T cells.
11  antigen-reactive lymphocytes mediated by T
(1 time)
Medicine
(1 time)
--- 2004 Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival.
12  autoantigen-reactive T
(1 time)
Allergy and Immunology
(1 time)
EAE (1 time)
2007 Regulatory T cell vaccination without autoantigen protects against experimental autoimmune encephalomyelitis.
13  D-related (HLA-DR) on monocytes was similar between groups; absolute T
(1 time)
Allergy and Immunology
(1 time)
HLA-DR (1 time)
IL (1 time)
PCT (1 time)
2010 Indication for a role of regulatory T cells for the advent of influenza A (H1N1)-related pneumonia.
14  down-regulation of GARP in T
(1 time)
Cell Biology
(1 time)
GARP (1 time)
LGALS3 (1 time)
2009 GARP: a key receptor controlling FOXP3 in human regulatory T cells.
15  family-related gene (GITR) expressed preferentially at high levels on T
(1 time)
Allergy and Immunology
(1 time)
GITR (1 time)
NIK (1 time)
2005 NF kappa B-inducing kinase deficiency results in the development of a subset of regulatory T cells, which shows a hyperproliferative activity upon glucocorticoid-induced TNF receptor family-related gene stimulation.
16  over-representation of its target genes in the T
(1 time)
Allergy and Immunology
(1 time)
COPD (1 time)
miRNA (1 time)
RT-PCR (1 time)
2014 Blunted expression of miR-199a-5p in regulatory T cells of patients with chronic obstructive pulmonary disease compared to unaffected smokers.
17  RA controls leukocyte homing and T
(1 time)
Science
(1 time)
RA (1 time)
2008 Retinoic acid in the immune system.
18  radioresistant endogenous T
(1 time)
Science
(1 time)
--- 2007 Full restoration of peripheral Foxp3+ regulatory T cell pool by radioresistant host cells in scurfy bone marrow chimeras.
19  RAG-1-competent transgenic animals (T/R(+)) remain healthy, protected by CD4(+) T
(1 time)
Science
(1 time)
EAE (1 time)
MBP (1 time)
TCR (1 time)
2002 Specificity requirements for selection and effector functions of CD25+4+ regulatory T cells in anti-myelin basic protein T cell receptor transgenic mice.
20  raising questions as to T
(1 time)
Medicine
(1 time)
--- 2010 CD25 appears non essential for human peripheral T(reg) maintenance in vivo.
21  range of other factors which may be impairing T
(1 time)
Medicine
(1 time)
--- 2009 Role of regulatory T-cells in autoimmunity.
22  rapidly emerging field of T
(1 time)
Science
(1 time)
RA (1 time)
2008 Retinoic acid in the immune system.
23  rare self-antigen-specific T
(1 time)
Allergy and Immunology
(1 time)
DC (1 time)
2006 Therapeutic potential of self-antigen-specific CD4+ CD25+ regulatory T cells selected in vitro from a polyclonal repertoire.
24  rate (GFR) and T
(1 time)
Medicine
(1 time)
CNI (1 time)
eGFR (1 time)
GFR (1 time)
2013 Deferred pre-emptive switch from calcineurin inhibitor to sirolimus leads to improvement in GFR and expansion of T regulatory cell population: a randomized, controlled trial.
25  rate was significantly lower in patients with high T
(1 time)
General Surgery
(1 time)
FOXP3 (1 time)
HCC (1 time)
HPF (1 time)
2007 Prognostic value of tumor-infiltrating FOXP3+ regulatory T cells in patients with hepatocellular carcinoma.
26  rates of conversion into IL-10-producing Foxp3(+)T
(1 time)
Allergy and Immunology
(1 time)
EAE (1 time)
2010 Central nervous system demyelinating disease protection by the human commensal Bacteroides fragilis depends on polysaccharide A expression.
27  rather suggest that polyclonal activation of T
(1 time)
Brain
(1 time)
EAE (1 time)
2006 Polyclonal expansion of regulatory T cells interferes with effector cell migration in a model of multiple sclerosis.
28  rather than focussing on intrinsic T
(1 time)
Medicine
(1 time)
--- 2009 Role of regulatory T-cells in autoimmunity.
29  rats by ex vivo-generated exogenous T
(1 time)
Science
(1 time)
EAMG (1 time)
MG (1 time)
2012 Regulatory T cell-based immunotherapies in experimental autoimmune myasthenia gravis.
30  readdressed the influence of GC therapy on T
(1 time)
Medicine
(1 time)
GCs (1 time)
2011 Influence of short-term glucocorticoid therapy on regulatory T cells in vivo.
31  receiving IL-2, the T
(1 time)
Medicine
(1 time)
IL (1 time)
2005 Lymphopenia and interleukin-2 therapy alter homeostasis of CD4+CD25+ regulatory T cells.
32  recent advances in our understanding of T
(1 time)
Allergy and Immunology
(1 time)
--- 2009 Regulatory T cells exert checks and balances on self tolerance and autoimmunity.
33  recent findings in T
(1 time)
Hematology
(1 time)
--- 2006 Regulatory T cells in cancer.
34  Recent investigations focusing on T
(1 time)
Neoplasms
(1 time)
GVHD (1 time)
GVL (1 time)
HCT (1 time)
2006 CD4+CD25+ regulatory T cells in human hematopoietic cell transplantation.
35  recent observations to suggest that T
(1 time)
Allergy and Immunology
(1 time)
--- 2012 Trafficking of regulatory T cells in the intestinal immune system.
36  recent studies suggest that T
(1 time)
Molecular Biology
(1 time)
FOXP3 (1 time)
2012 Functional stability of Foxp3+ regulatory T cells.
37  recently showed that prevalences of newly generated CD31-coexpressing naive T
(1 time)
Neurology
(1 time)
MS (1 time)
2008 Interferon beta-induced restoration of regulatory T-cell function in multiple sclerosis is prompted by an increase in newly generated naive regulatory T cells.
38  receptor signaling in natural T
(1 time)
Allergy and Immunology
(1 time)
SNPs (1 time)
2011 The p.Arg63Trp polymorphism controls Vav1 functions and Foxp3 regulatory T cell development.
39  receptor-specific agonist 2-pyridylethylamine dihydrochloride inhibited T
(1 time)
Allergy and Immunology
(1 time)
BMMC (1 time)
2009 Mast cells down-regulate CD4+CD25+ T regulatory cell suppressor function via histamine H1 receptor interaction.
40  receptors bypassed low-strength TCR signaling to drive the T
(1 time)
Allergy and Immunology
(1 time)
TCRs (1 time)
2013 Nr4a receptors are essential for thymic regulatory T cell development and immune homeostasis.
41  receptors on tumor-infiltrating T
(1 time)
Allergy and Immunology
(1 time)
conv (1 time)
CTLA-4 (1 time)
GITR (1 time)
2012 Tumor-infiltrating regulatory T cells delineated by upregulation of PD-1 and inhibitory receptors.
42  recipient synergizes with the effect of T
(1 time)
Medicine
(1 time)
--- 2010 CD4+CD25+ regulatory T cell depletion improves the graft-versus-tumor effect of donor lymphocytes after allogeneic hematopoietic stem cell transplantation.
43  recipients by favouring the induction of T
(1 time)
Endocrinology
(1 time)
MSCs (1 time)
2012 Mesenchymal stem cells differentially mediate regulatory T cells and conventional effector T cells to protect fully allogeneic islet grafts in mice.
44  recipients effectively suppressed allo-antigen driven T cell proliferation, but T
(1 time)
Allergy and Immunology
(1 time)
--- 2009 Fragile maintenance of allograft tolerance induced by lymphocyte sequestration and co-stimulation blockade.
45  recipients had higher percentages of T
(1 time)
General Surgery
(1 time)
AAV-HO-1 (1 time)
HO (1 time)
MLR (1 time)
2011 Hepatic overexpression of heme oxygenase-1 improves liver allograft survival by expanding T regulatory cells.
46  recognition by the T
(1 time)
Allergy and Immunology
(1 time)
EAE (1 time)
2001 Induction of a type 1 regulatory CD4 T cell response following V beta 8.2 DNA vaccination results in immune deviation and protection from experimental autoimmune encephalomyelitis.
47  recognition, discordant results were found in terms of T
(1 time)
Allergy and Immunology
(1 time)
FOXP3 (1 time)
IL (1 time)
TB (1 time)
2009 Characterization of regulatory T cells identified as CD4(+)CD25(high)CD39(+) in patients with active tuberculosis.
48  reconstituted with GZB-deficient T
(1 time)
Allergy and Immunology
(1 time)
GZB (1 time)
2008 Transplantation survival is maintained by granzyme B+ regulatory cells and adaptive regulatory T cells.
49  reconstituted with wild-type, perforin-deficient, or Fas ligand-deficient T
(1 time)
Allergy and Immunology
(1 time)
GZB (1 time)
2008 Transplantation survival is maintained by granzyme B+ regulatory cells and adaptive regulatory T cells.
50  recruitment and expansion of antigen-specific effector and T
(1 time)
Medicine
(1 time)
--- 2010 Intratumoral convergence of the TCR repertoires of effector and Foxp3+ CD4+ T cells.
51  reduce tumor infiltrating T
(1 time)
Gynecology
(1 time)
CTLs (1 time)
IPA (1 time)
2009 Ovarian cancer tumor infiltrating T-regulatory (T(reg)) cells are associated with a metastatic phenotype.
52  reduced number of lung T
(1 time)
Allergy and Immunology
(1 time)
PLN (1 time)
TNF-alpha (1 time)
2012 Failure to recruit anti-inflammatory CD103+ dendritic cells and a diminished CD4+ Foxp3+ regulatory T cell pool in mice that display excessive lung inflammation and increased susceptibility to Mycobacterium tuberculosis.
53  reduced the generation of induced T
(1 time)
Allergy and Immunology
(1 time)
IBD (1 time)
2011 Critical role of Bcl11b in suppressor function of T regulatory cells and prevention of inflammatory bowel disease.
54  reduced the suppressive function of TGF-beta-induced T
(1 time)
Medicine
(1 time)
NSCLC (1 time)
TGF-beta (1 time)
2010 PGE(2) contributes to TGF-beta induced T regulatory cell function in human non-small cell lung cancer.
55  reduced-intensity conditioning-induced T
(1 time)
Science
(1 time)
BM (1 time)
HvG (1 time)
2007 Low-intensity transplant regimens facilitate recruitment of donor-specific regulatory T cells that promote hematopoietic engraftment.
56  reducing human T
(1 time)
Allergy and Immunology
(1 time)
PBMCs (1 time)
2006 Selective elimination of human regulatory T lymphocytes in vitro with the recombinant immunotoxin LMB-2.
57  reducing the need to directly target T
(1 time)
Medicine
(1 time)
DCs (1 time)
2008 A20 is an antigen presentation attenuator, and its inhibition overcomes regulatory T cell-mediated suppression.
58  redundant genetic switch thus 'locked in' the T
(1 time)
Allergy and Immunology
(1 time)
--- 2012 A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells.
59  regard to human T
(1 time)
Medicine
(1 time)
regs (2 times)
2012 CD25 blockade depletes and selectively reprograms regulatory T cells in concert with immunotherapy in cancer patients.
60  regarding the mechanisms underlying T
(1 time)
Allergy and Immunology
(1 time)
--- 2008 The Foxp3+ regulatory T cell: a jack of all trades, master of regulation.
61  regardless of T
(1 time)
Allergy and Immunology
(1 time)
TSHR (1 time)
WT (1 time)
2008 Role of the transgenic human thyrotropin receptor A-subunit in thyroiditis induced by A-subunit immunization and regulatory T cell depletion.
62  regenerating protein 1-alpha
(1 time)
Allergy and Immunology
(1 time)
PSP (1 time)
2014 Pancreatic stone protein - a possible biomarker of multiorgan failure and mortality in children sepsis.
63  reggae
(1 time)
Cardiology
(1 time)
zERG (1 time)
2008 Deficient zebrafish ether-a-go-go-related gene channel gating causes short-QT syndrome in zebrafish reggae mutants.
64  region (TSDR) indicating that they were not of nT
(1 time)
Allergy and Immunology
(1 time)
ASC (1 time)
FOXP3 (1 time)
IL (1 time)
2013 Human adipose-tissue derived mesenchymal stem cells induce functional de-novo regulatory T cells with methylated FOXP3 gene DNA.
65  regional lymph node and the T
(1 time)
Transplantation
(1 time)
MC (1 time)
2009 Mast cell degranulation breaks peripheral tolerance.
66  regular menses
(1 time)
Endocrinology
(1 time)
olig (1 time)
PCOS (1 time)
1993 The relationship of insulin insensitivity to menstrual pattern in women with hyperandrogenism and polycystic ovaries.
67  regular parts R
(1 time)
Physics
(1 time)
osc (2 times)
2005 Asymptotical forms of canonical mappings near separatrix of Hamiltonian systems.
68  regular, R
(1 time)
Physics
(1 time)
osc (2 times)
2005 Asymptotical forms of canonical mappings near separatrix of Hamiltonian systems.
69  regulate both pathogenic and T
(1 time)
Allergy and Immunology
(1 time)
--- 2012 The dual effects of B cell depletion on antigen-specific T cells in BDC2.5NOD mice.
70  regulate diabetogenesis, but temporal alterations in nT
(1 time)
Endocrinology
(1 time)
--- 2007 Functional waning of naturally occurring CD4+ regulatory T-cells contributes to the onset of autoimmune diabetes.
71  regulated by iNKT or T
(1 time)
Microbiology
(1 time)
CMV (1 time)
MCMV (1 time)
NK (1 time)
2011 Salivary gland NK cells are phenotypically and functionally unique.
72  regulated by T
(1 time)
Hematology
(1 time)
APCs (1 time)
DLI (1 time)
GVH (1 time)
2006 Graft-versus-leukemia and graft-versus-host reactions after donor lymphocyte infusion are initiated by host-type antigen-presenting cells and regulated by regulatory T cells in early and long-term chimeras.
73  regulated DC and T
(1 time)
Immune System Diseases
(1 time)
DCs (1 time)
2012 Functional crosstalk between dendritic cells and Foxp3(+) regulatory T cells in the maintenance of immune tolerance.
74  regulated the expression of additional T
(1 time)
Allergy and Immunology
(1 time)
TGF-beta (1 time)
2010 Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells.
75  regulates both T
(1 time)
Science
(1 time)
AhR (1 time)
2008 Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor.
76  regulates T-cell responses by induction of T
(1 time)
Toxicology
(1 time)
AhR (1 time)
PE (1 time)
TCDD (1 time)
2011 Activation of the aryl hydrocarbon receptor suppresses sensitization in a mouse peanut allergy model.
77  regulates the development of nT
(1 time)
Signal Transduction
(1 time)
DAG (1 time)
ERK (1 time)
TCR (1 time)
2013 Diacylglycerol kinase zeta limits the generation of natural regulatory T cells.
78  regulates the differentiation of natural T
(1 time)
Science
(1 time)
--- 2010 The ligase PIAS1 restricts natural regulatory T cell differentiation by epigenetic repression.
79  regulating integrin signaling and T
(1 time)
Signal Transduction
(1 time)
--- 2012 Lack of the phosphatase PTPN22 increases adhesion of murine regulatory T cells to improve their immunosuppressive function.
80  regulating T
(1 time)
Allergy and Immunology
(1 time)
GITR (1 time)
NIK (1 time)
2005 NF kappa B-inducing kinase deficiency results in the development of a subset of regulatory T cells, which shows a hyperproliferative activity upon glucocorticoid-induced TNF receptor family-related gene stimulation.
81  regulating tDC-mediated T
(1 time)
Allergy and Immunology
(1 time)
Ab (1 time)
DLL4 (1 time)
Flt3 (1 time)
2012 Dll4-Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice.
82  regulation mediated by T
(1 time)
Allergy and Immunology
(1 time)
HCV (1 time)
HIV (1 time)
2008 CD8+ regulatory T cells in persistent human viral infections.
83  regulation of conjunctiva-resident nT
(1 time)
Ophthalmology
(1 time)
eff (1 time)
HSV (1 time)
LTA (1 time)
2011 Engagement of TLR2 reverses the suppressor function of conjunctiva CD4+CD25+ regulatory T cells and promotes herpes simplex virus epitope-specific CD4+CD25- effector T cell responses.
84  regulation of the susceptibility to T
(1 time)
Science
(1 time)
APC (1 time)
DC (1 time)
2009 Regulatory T cell differentiation of thymocytes does not require a dedicated antigen-presenting cell but is under T cell-intrinsic developmental control.
85  regulator', the emerging view is one of T
(1 time)
Allergy and Immunology
(1 time)
--- 2009 Foxp3+ regulatory T cells: differentiation, specification, subphenotypes.
86  regulators for pT
(1 time)
Biology
(1 time)
EAE (1 time)
TCR (1 time)
2015 MicroRNA-31 negatively regulates peripherally derived regulatory T-cell generation by repressing retinoic acid-inducible protein 3.
87  regulatory cytokine and T
(1 time)
Parasitology
(1 time)
DAI (1 time)
DSS (1 time)
MLN (1 time)
2012 Trichinella spiralis infection suppressed gut inflammation with CD4(+)CD25(+)Foxp3(+) T cell recruitment.
88  regulatory DCs, which can further expand the T
(1 time)
Chemistry
(1 time)
DCs (1 time)
IDO (1 time)
2011 Using an ancient tool for igniting and propagating immune tolerance: IDO as an inducer and amplifier of regulatory T cell functions.
89  regulatory mechanisms by T
(1 time)
Allergy and Immunology
(1 time)
BM (1 time)
LP (1 time)
2007 Expression of CTLA-4 and FOXP3 in cis protects from lethal lymphoproliferative disease.
90  regulatory mechanisms of these nT
(1 time)
Ophthalmology
(1 time)
eff (1 time)
HSV (1 time)
LTA (1 time)
2011 Engagement of TLR2 reverses the suppressor function of conjunctiva CD4+CD25+ regulatory T cells and promotes herpes simplex virus epitope-specific CD4+CD25- effector T cell responses.
91  regulatory network of human T
(1 time)
Blood Transfusion
(1 time)
--- 2009 Perspectives on Regulatory T Cell Therapies.
92  regulatory network together with the natural T
(1 time)
Allergy and Immunology
(1 time)
aGVHD (1 time)
GVHD (1 time)
PSC (1 time)
2008 Soluble human leucocyte antigen-G molecules in peripheral blood haematopoietic stem cell transplantation: a specific role to prevent acute graft-versus-host disease and a link with regulatory T cells.
93  regulatory T cell activity or to identify T
(1 time)
Allergy and Immunology
(1 time)
--- 2006 Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells.
94  rejection through a process involving T
(1 time)
Endocrinology
(1 time)
FVB (1 time)
MST (1 time)
2012 Intravenous infusion of donor apoptotic leukocytes before transplantation delays allogeneic islet graft rejection through regulatory T cells.
95  related to the impaired in vivo function of naturally occurring T
(1 time)
Allergy and Immunology
(1 time)
--- 2009 Notch3 and pTalpha/pre-TCR sustain the in vivo function of naturally occurring regulatory T cells.
96  relative enrichment of tumour-infiltrating T
(1 time)
Allergy and Immunology
(1 time)
IL (1 time)
2010 Involvement of T helper type 17 and regulatory T cell activity in tumour immunology of bladder carcinoma.
97  relative frequency of circulating T
(1 time)
Medicine
(1 time)
GCs (1 time)
2011 Influence of short-term glucocorticoid therapy on regulatory T cells in vivo.
98  relatively severe allergic disease, adaptive and functional T
(1 time)
Allergy and Immunology
(1 time)
FOXP3 (1 time)
IL (1 time)
2007 The levels of CD4+CD25+ regulatory T cells in paediatric patients with allergic rhinitis and bronchial asthma.
99  relevance of HIF-1alpha and Hox, in general, for nT
(1 time)
Allergy and Immunology
(1 time)
--- 2014 HIF-1alpha- and hypoxia-dependent immune responses in human CD4+CD25high T cells and T helper 17 cells.
100  remain critical in developing therapeutics targeting T
(1 time)
Allergy and Immunology
(1 time)
--- 2011 Safety assessment of immunomodulatory biologics: the promise and challenges of regulatory T-cell modulation.