| 1 |
short hairpin RNA
(3770 times)
|
Neoplasms
(913 times)
|
RNAi (448 times)
siRNA (295 times)
HCC (109 times)
|
2003 Lentiviral-mediated RNA interference.
|
| 2 |
short hairpin ribonucleic acid
(37 times)
|
Neoplasms
(8 times)
|
DNA (3 times)
siRNA (3 times)
ALDH1 (2 times)
|
2007 Noxa/Mcl-1 balance regulates susceptibility of cells to camptothecin-induced apoptosis.
|
| 3 |
short hairpin interfering RNA
(29 times)
|
Biochemistry
(5 times)
|
BrdU (2 times)
CNS (2 times)
CSCs (2 times)
|
2004 Major histocompatibility class II transactivator (CIITA) mediates repression of collagen (COL1A2) transcription by interferon gamma (IFN-gamma).
|
| 4 |
short hairpin RNA interference
(7 times)
|
Biochemistry
(4 times)
|
EGFR (2 times)
VSMCs (2 times)
alpha-SMA (1 time)
|
2006 Hepatic knockdown of mitochondrial GPAT1 in ob/ob mice improves metabolic profile.
|
| 5 |
small hairpin
(7 times)
|
Molecular Biology
(2 times)
|
GFP (2 times)
AAV (1 time)
Abs (1 time)
|
2005 Knockdown of STAT3 expression by RNA interference inhibits the induction of breast tumors in immunocompetent mice.
|
| 6 |
lentivirus-short hairpin RNA
(5 times)
|
Pharmacology
(2 times)
|
APOE (1 time)
CAD (1 time)
con (1 time)
|
2011 Silencing oncogene expression in cervical cancer stem-like cells inhibits their cell growth and self-renewal ability.
|
| 7 |
short RNA
(3 times)
|
Molecular Biology
(1 time)
|
tkRNAi (2 times)
qRT-PCR (1 time)
|
2008 Transkingdom RNA interference (tkRNAi): a novel method to induce therapeutic gene silencing.
|
| 8 |
short hairpin RNA inhibition
(2 times)
|
Cell Biology
(2 times)
|
ARPKD (1 time)
Bic-C (1 time)
ERK (1 time)
|
2005 Inhibition of Pkhd1 impairs tubulomorphogenesis of cultured IMCD cells.
|
| 9 |
short hairpin-induced
(2 times)
|
Cardiology
(1 time)
|
FLIP (1 time)
IR (1 time)
|
2003 FLIP protects cardiomyocytes from apoptosis induced by simulated ischemia/reoxygenation, as demonstrated by short hairpin-induced (shRNA) silencing of FLIP mRNA.
|
| 10 |
short hairpin-type RNAi constructs
(2 times)
|
Transplantation
(1 time)
|
RNAi (2 times)
HLA (1 time)
HSC (1 time)
|
2006 Permanent, lowered HLA class I expression using lentivirus vectors with shRNA constructs: Averting cytotoxicity by alloreactive T lymphocytes.
|
| 11 |
short-interfering RNA
(2 times)
|
Neoplasms
(1 time)
|
AP-1 (1 time)
BDNF (1 time)
BM (1 time)
|
2010 Lentiviral shRNA silencing of BDNF inhibits in vivo multiple myeloma growth and angiogenesis via down-regulated stroma-derived VEGF expression in the bone marrow milieu.
|
| 12 |
silencing hairpin RNA
(2 times)
|
Molecular Biology
(2 times)
|
CO (1 time)
HO (1 time)
MMP-2 (1 time)
|
2009 Bacterial delivery of siRNAs: a new approach to solid tumor therapy.
|
| 13 |
small inhibitory hairpin RNA
(2 times)
|
Biophysics
(1 time)
|
IFN (1 time)
LPS (1 time)
Lrrk2-KD (1 time)
|
2012 Impaired inflammatory responses in murine Lrrk2-knockdown brain microglia.
|
| 14 |
survivin-short hairpin RNA
(2 times)
|
Allergy and Immunology
(1 time)
|
FCM (1 time)
MTT (1 time)
RT-PCR (1 time)
|
2008 Knockdown of Mgat5 inhibits breast cancer cell growth with activation of CD4+ T cells and macrophages.
|
| 15 |
UMUC3-control-short hairpin RNA
(2 times)
|
Oncogenes
(1 time)
|
AR (2 times)
CpdA (1 time)
GCs (1 time)
|
2015 Compound A Inhibits Bladder Cancer Growth Predominantly via Glucocorticoid Receptor Transrepression.
|
| 16 |
(LINGO-1)-short hairpin interfering RNA
(1 time)
|
Biotechnology
(1 time)
|
BPA (1 time)
CNS (1 time)
LINGO-1 (1 time)
|
2019 LINGO-1 shRNA Loaded by Pluronic F-127 Promotes Functional Recovery After Ventral Root Avulsion.
|
| 17 |
(LV)-TWEAK-short hairpin RNA
(1 time)
|
Rheumatology
(1 time)
|
ER (1 time)
LV (1 time)
PBMCs (1 time)
|
2016 Estrogen-induced expression of tumor necrosis factor-like weak inducer of apoptosis through ERalpha accelerates the progression of lupus nephritis.
|
| 18 |
AAV-scrambled-short hairpin RNA
(1 time)
|
Neurology
(1 time)
|
AAV (1 time)
CBCs (1 time)
GlyR (1 time)
|
2014 Adeno-associated virus-RNAi of GlyRalpha1 and characterization of its synapse-specific inhibition in OFF alpha transient retinal ganglion cells.
|
| 19 |
Aurora-A-short hairpin RNA
(1 time)
|
Molecular Biology
(1 time)
|
---
|
2004 Overexpression of Aurora-A potentiates HRAS-mediated oncogenic transformation and is implicated in oral carcinogenesis.
|
| 20 |
CCR3-short hairpin
(1 time)
|
Clinical Laboratory Techniques
(1 time)
|
AR (1 time)
CCK-8 (1 time)
CCR3 (1 time)
|
2020 CCR3-shRNA promotes apoptosis and inhibits chemotaxis and degranulation of mouse mast cells.
|
| 21 |
lenti-small hairpin RNA
(1 time)
|
Ophthalmology
(1 time)
|
CCT (1 time)
siRNA (1 time)
|
2014 CD147 required for corneal endothelial lactate transport.
|
| 22 |
Neo-SOCS-1small hairpin RNA
(1 time)
|
Pediatrics
(1 time)
|
GLUT4 (1 time)
HOMA-IR (1 time)
IRS (1 time)
|
2011 The influence of down-regulation of suppressor of cellular signaling proteins by RNAi on glucose transport of intrauterine growth retardation rats.
|
| 23 |
osteopontin-short-hairpin RNA
(1 time)
|
Neoplasms
(1 time)
|
ESCC (1 time)
|
2006 An inducible short-hairpin RNA vector against osteopontin reduces metastatic potential of human esophageal squamous cell carcinoma in vitro and in vivo.
|
| 24 |
pIRAK-M-short hairpin RNA
(1 time)
|
General Surgery
(1 time)
|
ET (1 time)
IRAK-M (1 time)
KCs (1 time)
|
2008 Up-regulation of IRAK-M is essential for endotoxin tolerance induced by a low dose of lipopolysaccharide in Kupffer cells.
|
| 25 |
PPARgamma-small hairpin RNA
(1 time)
|
Neurology
(1 time)
|
FNS (1 time)
PPARgamma (1 time)
SD (1 time)
|
2016 Electrical stimulation of cerebellar fastigial nucleus protects against cerebral ischemic injury by PPARgamma upregulation.
|
| 26 |
seen with DHODH RNA interference
(1 time)
|
Biology
(1 time)
|
BQR (1 time)
|
2018 Synergistic inhibition of melanoma xenografts by Brequinar sodium and Doxorubicin.
|
| 27 |
short hairpin oligoes
(1 time)
|
Neoplasms
(1 time)
|
RT-PCR (1 time)
|
2010 Effects of shRNA targeting maspin on invasion of gastric carcinoma SGC7901 cell line.
|
| 28 |
short hairpin precursors
(1 time)
|
Clinical Laboratory Techniques
(1 time)
|
ESI-MS (1 time)
RNAi (1 time)
siRNA (1 time)
|
2008 An ESI-MS method for characterization of native and modified oligonucleotides used for RNA interference and other biological applications.
|
| 29 |
short hairpin RNA expression vector
(1 time)
|
Biomedical Engineering
(1 time)
|
AD (1 time)
CDE (1 time)
|
2022 Multifunctional Therapeutic Cyclodextrin-Appended Dendrimer Complex for Treatment of Systemic and Localized Amyloidosis.
|
| 30 |
short hairpin RNA lentivirals
(1 time)
|
Cell Biology
(1 time)
|
AKI (1 time)
ALR (1 time)
GSH-GPx (1 time)
|
2019 Augmenter of liver regeneration protects the kidney from ischaemia-reperfusion injury in ferroptosis.
|
| 31 |
short hairpin RNA library
(1 time)
|
|
CAM (1 time)
|
2019 Intravital imaging tumor screen used to identify novel metastasis-blocking therapeutic targets.
|
| 32 |
short hairpin RNA recombinant vector
(1 time)
|
Therapeutics
(1 time)
|
AI (1 time)
PCNA (1 time)
PI (1 time)
|
2008 Induced apoptosis with ultrasound-mediated microbubble destruction and shRNA targeting survivin in transplanted tumors.
|
| 33 |
short hairpin-structured RNA
(1 time)
|
Neoplasms
(1 time)
|
AAV (1 time)
AR (1 time)
|
2009 Adeno-associated virus-delivered short hairpin-structured RNA for androgen receptor gene silencing induces tumor eradication of prostate cancer xenografts in nude mice: a preclinical study.
|
| 34 |
short interference RNA
(1 time)
|
Genetics, Medical
(1 time)
|
DMBT1 (1 time)
HNEpC (1 time)
STAT3 (1 time)
|
2017 Silenced DMBT1 promotes nasal mucosa epithelial cell growth.
|
| 35 |
short specific sequence of RNA
(1 time)
|
Neoplasms
(1 time)
|
CRC (1 time)
IQGAP1 (1 time)
|
2022 Novel Approach Using shRNA of IQGAP1 for Colon Cancer Therapy: HCT116 as a Surrogate Model Colorectal Carcinoma
|
| 36 |
show that the administration of an anticatalase
(1 time)
|
Substance-Related Disorders
(1 time)
|
ADE (1 time)
EtOH (1 time)
VTA (1 time)
|
2013 The alcohol deprivation effect: marked inhibition by anticatalase gene administration into the ventral tegmental area in rats.
|
| 37 |
showed that dhh blockade via either adenovirus-mediated
(1 time)
|
Neurology
(1 time)
|
DHH (1 time)
|
2015 Desert hedgehog is a mediator of demyelination in compression neuropathies.
|
| 38 |
Silencing autophagy inhibitors CQ/3-MA and LC3
(1 time)
|
Toxicology
(1 time)
|
AVOs (1 time)
FKB (1 time)
|
2017 Chalcone flavokawain B induces autophagic-cell death via reactive oxygen species-mediated signaling pathways in human gastric carcinoma and suppresses tumor growth in nude mice.
|
| 39 |
silencing of PHB expression by adenoviral small interfering RNA
(1 time)
|
Biochemistry
(1 time)
|
Ad (1 time)
GC (1 time)
PHB (1 time)
|
2011 Prohibitin (PHB) acts as a potent survival factor against ceramide induced apoptosis in rat granulosa cells.
|
| 40 |
Since hairpin small interference RNA
(1 time)
|
Genetics, Medical
(1 time)
|
Ad (1 time)
HD (1 time)
HTT (1 time)
|
2005 Adenovirus-mediated silencing of huntingtin expression by shRNA.
|
| 41 |
single hairpin
(1 time)
|
Biochemistry
(1 time)
|
CRF (1 time)
PDZ (1 time)
SAP97 (1 time)
|
2013 Role of SAP97 protein in the regulation of corticotropin-releasing factor receptor 1 endocytosis and extracellular signal-regulated kinase 1/2 signaling.
|
| 42 |
Smad4-short hairpin
(1 time)
|
Biochemistry
(1 time)
|
ADM (1 time)
mRNA (1 time)
TGF-beta (1 time)
|
2019 Smad4 gene silencing enhances the chemosensitivity of human lymphoma cells to adriamycin via inhibition of the activation of transforming growth factor beta signaling pathway.
|
| 43 |
small hairpin interference ribonucleic acid
(1 time)
|
General Surgery
(1 time)
|
MDR (1 time)
mRNA (1 time)
MTT (1 time)
|
2009 Reverse multidrug resistance in laryngeal cancer cells by knockdown MDR1 gene expression.
|
| 44 |
small hairpin interfering RNA molecules to TREM-1
(1 time)
|
Pulmonary Medicine
(1 time)
|
TLR (1 time)
TREM-1 (1 time)
|
2007 Functional genomics of silencing TREM-1 on TLR4 signaling in macrophages.
|
| 45 |
small hairpin RNA molecules
(1 time)
|
Virology
(1 time)
|
SARS (1 time)
SARS-CoV (1 time)
|
2006 Inhibition of SARS-CoV gene expression by adenovirus-delivered small hairpin RNA.
|
| 46 |
small heteroduplex RNA
(1 time)
|
Allergy and Immunology
(1 time)
|
dsRNA (1 time)
IFN (1 time)
mDCs (1 time)
|
2013 The interaction between the helicase DHX33 and IPS-1 as a novel pathway to sense double-stranded RNA and RNA viruses in myeloid dendritic cells.
|
| 47 |
SSCloAldebr cells using ashort hairpin RNA
(1 time)
|
Neoplasms
(1 time)
|
---
|
2013 The role Hiwi gene in the maintenance of lung cancer stem cell populations.
|
| 48 |
such as reporter gene assay, gene over-expression, gene knock down
(1 time)
|
Biology
(1 time)
|
GFP (1 time)
|
2012 In ovo electroporation in embryonic chick retina.
|
| 49 |
UMUC3-AR-short hairpin RNA
(1 time)
|
Neoplasms
(1 time)
|
AR (1 time)
|
2016 Enzalutamide inhibits androgen receptor-positive bladder cancer cell growth.
|
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